Os<scp>CERK</scp>1 plays a crucial role in the lipopolysaccharide‐induced immune response of rice

Desaki, Yoshitake; Kouzai, Yusuke; Ninomiya, Yusuke; Iwase, Ryosuke; Shimizu, Yumi; Seko, Keito; Molinaro, Antonio; Minami, Eiichi; Shibuya, Naoto; Kaku, Hanae; Nishizawa, Yuji

doi:10.1111/nph.14941

Cited by 67 publications

(53 citation statements)

References 52 publications

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“…Thus far, LORE homologs are confined to the Brassicaceae family, hence other undefined receptors are likely to be responsible for sensing LPS, or similar metabolites, in other plant families. In rice (Oryza sativa), OsCERK1, the receptor for chitin oligomers and peptidoglycan, also appears to mediate sensing of LPS from several bacterial species, including P. aeruginosa [56]. However, whether LPS is the specific ligand of this receptor has not been shown and requires further investigation.…”

Section: Animal and Plant Receptors Recognize Lps And Mount An Immunementioning

confidence: 99%

The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology

2019

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The major constituent of the outer membrane of Gram-negative bacteria is lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O antigen, which is a long polysaccharide chain extending into the extracellular environment. Due to the localization of LPS, it is a key molecule on the bacterial cell wall that is recognized by the host to deploy an immune defence in order to neutralize invading pathogens. However, LPS also promotes bacterial survival in a host environment by protecting the bacteria from these threats. This review explores the relationship between the different LPS glycoforms of the opportunistic pathogen Pseudomonas aeruginosa and the ability of this organism to cause persistent infections, especially in the genetic disease cystic fibrosis. We also discuss the role of LPS in facilitating biofilm formation, antibiotic resistance, and how LPS may be targeted by new antimicrobial therapies.

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Section: Animal and Plant Receptors Recognize Lps And Mount An Immunementioning

confidence: 99%

The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology

2019

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“…Lastly, a recent study has reported OsCERK1, the chitin co-receptor, as an LPS receptor/co-receptor in rice, but not in A. thaliana [137]. This indicates a significant difference between LPS perception in rice and Arabidopsis.…”

Section: Lps Perceptionmentioning

confidence: 91%

Prospects of Gene Knockouts in the Functional Study of MAMP-Triggered Immunity: A Review

Offor

Dubery

Piater

2020

IJMS

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Plants depend on both preformed and inducible defence responses to defend themselves against biotic stresses stemming from pathogen attacks. In this regard, plants perceive pathogenic threats from the environment through pattern recognition receptors (PRRs) that recognise microbe-associated molecular patterns (MAMPs), and so induce plant defence responses against invading pathogens. Close to thirty PRR proteins have been identified in plants, however, the molecular mechanisms underlying MAMP perception by these receptors/receptor complexes are not fully understood. As such, knockout (KO) of genes that code for PRRs and co-receptors/defence-associated proteins is a valuable tool to study plant immunity. The loss of gene activity often causes changes in the phenotype of the model plant, allowing in vivo studies of gene function and associated biological mechanisms. Here, we review the functions of selected PRRs, brassinosteroid insensitive 1 (BRI1) associated receptor kinase 1 (BAK1) and other associated defence proteins that have been identified in plants, and also outline KO lines generated by T-DNA insertional mutagenesis as well as the effect on MAMP perception—and triggered immunity (MTI). In addition, we further review the role of membrane raft domains in flg22-induced MTI in Arabidopsis, due to the vital role in the activation of several proteins that are part of the membrane raft domain theory in this regard.

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“…Finally, OsCERK1 , but not AtCERK1 , was recently shown to be involved in perception of LPS, which is also not a GlcNAc-containing molecules ( Desaki et al, 2018 ).…”

Section: Phylogenetic Analysismentioning

confidence: 99%

LysM Receptor-Like Kinase and LysM Receptor-Like Protein Families: An Update on Phylogeny and Functional Characterization

et al. 2018

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Members of plant specific families of receptor-like kinases (RLKs) and receptor-like proteins (RLPs), containing 3 extracellular LysMs have been shown to directly bind and/or to be involved in perception of lipo-chitooligosaccharides (LCO), chitooligosaccharides (CO), and peptidoglycan (PGN), three types of GlcNAc-containing molecules produced by microorganisms. These receptors are involved in microorganism perception by plants and can activate different plant responses leading either to symbiosis establishment or to defense responses against pathogens. LysM-RLK/Ps belong to multigenic families. Here, we provide a phylogeny of these families in eight plant species, including dicotyledons and monocotyledons, and we discuss known or putative biological roles of the members in each of the identified phylogenetic groups. We also report and discuss known biochemical properties of the LysM-RLK/Ps.

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OsCERK1 plays a crucial role in the lipopolysaccharide‐induced immune response of rice

Cited by 67 publications

References 52 publications

The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology

The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology

Prospects of Gene Knockouts in the Functional Study of MAMP-Triggered Immunity: A Review

LysM Receptor-Like Kinase and LysM Receptor-Like Protein Families: An Update on Phylogeny and Functional Characterization

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