Outbreak of novel influenza A (H1N1) in an adult haematology department and haematopoietic cell transplantation unit: Clinical presentation and outcome

The clinical features and outcome of 2009 H1N1 influenza infection in allo-SCT patients: a British Society of Blood and Marrow Transplantation study

“…In a smaller report of nosocomial H1N1 infection in eight patients in a haematology unit, three cases were identified in allograft recipients; all presented with fever and upper respiratory tract infection symptoms, two (66%) of the SCT patients were admitted to ICU with pneumonia and both died. 18 The clinical presenting features described in our study parallel those seen with 2009 H1N1 influenza in immunocompetent patients. [19][20][21] However, life-threatening complications and mortality occurred at a higher frequency than in the general population, where around 9% were hospitalised 20 and the case fatality rate was 26 per 100 000.…”

Genotyping of a nosocomial outbreak of pandemic influenza A/H1N1 2009

“…Several reports have focused on transmission events involving influenza A (H1N1) 2009, [11][12][13] and even on events involving high-risk resistant and/or virulent influenza A (H1N1) 2009 variants. 5,14,15 In addition to the interest in identifying the transmission of high-risk variants, the survey of transmission events by the new pandemic variant is relevant from an epidemiological point of view.…”

Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients

“…Pandemic H1N1 has been described in HCT recipients and oncology patients from several studies and case series ( Table 3 ). Case-fatality rates have ranged from 0 to 38% in various cohorts [95, 98-102, 104, 105]. …”