Outcome of Psychoanalytic and Cognitive-Behavioural Long-Term Therapy with Chronically Depressed Patients: A Controlled Trial with Preferential and Randomized Allocation

Leuzinger‐Bohleber, Marianne; Hautzinger, Martin; Fiedler, Georg Martin; Keller, Wolfram; Bahrke, Ulrich; Kallenbach, Lisa; Kaufhold, Johannes; Ernst, Mareike; Negele, Alexa; Schoett, Margerete J S; Küchenhoff, Helmut; Günther, Felix; Rüger, Bernhard; Beutel, Manfred E.

doi:10.1177/0706743718780340

Cited by 71 publications

(44 citation statements)

References 43 publications

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“…This is the overall effect; the effect size that she found for symptom improvement (as opposed to personality change) at termination was 1.03 for long-term therapy, and for psychoanalysis it was 1.38. A subsequent study by Leuzinger-Bohleber et al (2018, in press) shows even bigger effect sizes: between 1.62 and 1.89 after 3 years of treatment. These are enormous effects.…”

Section: Claimmentioning

confidence: 86%

The Neurobiological Underpinnings of Psychoanalytic Theory and Therapy

Solms

2018

Front. Behav. Neurosci.

122

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This paper sets out the neurobiological underpinnings of the core theoretical claims of psychoanalysis. These claims concern (1) innate emotional needs, (2) learning from experience, and (3) unconscious mental processing. The paper also considers the neurobiological underpinnings of the mechanisms of psychoanalytic treatment—a treatment which is based on the aforementioned claims. Lastly, it reviews the available empirical evidence concerning the therapeutic efficacy of this form of treatment.

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Section: Claimmentioning

confidence: 86%

The Neurobiological Underpinnings of Psychoanalytic Theory and Therapy

Solms

2018

Front. Behav. Neurosci.

122

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“…Long‐term psychoanalytic psychotherapy over 18 months was compared treatment as usual in a sample of adults with TRD, and while differences were not apparent at the end of the treatment phase, they emerged during the 24‐, 30‐, and 42‐month follow‐ups, with improvements in both the clinical and functional outcomes of patients who received psychoanalytic therapy (Fonagy et al, ). An additional study of chronically depressed adults in Germany compared long‐term psychoanalytic therapy (36 months) with long‐term CBT (15 months) and found significant reduction in depressive symptoms in both groups (Leuzinger‐Bohleber et al, ).…”

Section: Strategies For Treatment‐resistant Depressionmentioning

confidence: 99%

“…Grade both the clinical and functional outcomes of patients who received psychoanalytic therapy (Fonagy et al, 2015). An additional study of chronically depressed adults in Germany compared long-term psychoanalytic therapy (36 months) with long-term CBT (15 months) and found significant reduction in depressive symptoms in both groups (Leuzinger-Bohleber et al, 2019).…”

Section: Psychotherapy Augmentation Strategiesmentioning

confidence: 99%

Annual Research Review: Defining and treating pediatric treatment‐resistant depression

Dwyer

Stringaris

Brent

et al. 2020

Child Psychology Psychiatry

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Background Adolescent major depressive disorder (MDD) is a significant health problem, associated with substantial morbidity, cost, and mortality. Depression is a significant risk factor for suicide, which is now the second leading cause of death in young people. Up to twenty per cent of adolescents will experience MDD before adulthood, and while a substantial proportion will improve with standard‐of‐care treatments (psychotherapy and medication), roughly one third will not. Methods Here, we have reviewed the literature in order to discuss the concept of treatment‐resistant depression (TRD) in adolescence, examine risk factors, diagnostic difficulties, and challenges in evaluating symptom improvement, and providing guidance on how to define adequate medication and psychotherapy treatment trials. Results We propose a staging model for adolescent TRD and review the treatment literature. The evidence base for first‐ and second‐line treatments primarily derives from four large pediatric clinical trials (TADS, TORDIA, ADAPT, and IMPACT). After two medications and a trial of evidence‐based psychotherapy have failed to alleviate depressive symptoms, the evidence becomes quite thin for subsequent treatments. Here, we review the evidence for the effectiveness of medication switches, medication augmentation, psychotherapy augmentation, and interventional treatments (i.e., transcranial magnetic stimulation, electroconvulsive therapy, and ketamine) for adolescent TRD. Comparisons are drawn to the adult TRD literature, and areas for future pediatric depression research are highlighted. Conclusions As evidence is limited for treatments in this population, a careful consideration of the known risks and side effects of escalated treatments (e.g., mood stabilizers and atypical antipsychotics) is warranted and weighed against potential, but often untested, benefits.

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“…Shedler (2010), basándose en una revisión estudios de resultados, señala que la ventaja de la intervención psicoanalítica sobre otros modelos reside en que sus beneficios parecerían extenderse más allá del término de la intervención e incluirían cambios en los mecanismos estructurales de base, como por ejemplo, en la función reflexiva o capacidad para mentalizar. Un estudio reciente realizado en Alemania mostró que las terapias psicoanalíticas a largo plazo para la depresión si bien mostraron resultados similares a los obtenidos por la terapia cognitivo conductual en reducción de sintomatología, evidenciaron cambios estructurales en las fases de seguimiento post intervención (Leuzinger-Bohleber et al, 2019). Estos resultados reconducen a viejas inferencias hechas en el marco clínico sobre cómo el paciente internaliza aspectos de la función analítica del terapeuta que luego utiliza como modelo interno de reflexión y elaboración (Lemma, 2016).…”

Section: Moments Importants Associés Au Changement Psychiqueunclassified

Momentos significativos asociados al cambio psíquico

Lagos

Koroleff

2021

PSICO

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Esta investigación se propuso los siguientes objetivos: 1) identificar, tematizar y describir los momentos significativos de un proceso psicoanalítico percibidos por los pacientes como importantes para el cambio psíquico, así como analizar su naturaleza y las relaciones entre estos, y los diferentes aspectos del proceso psicoanalítico; 2) evaluar si la perspectiva de los usuarios sobre los momentos significativos del proceso psicoterapéutico asociados al cambio contribuye a ampliar la comprensión de la acción terapéutica de la psicoterapia psicoanalítica. El proyecto es de enfoque cualitativo, pues se tomó como información un fenómeno subjetivo (Mortl & Gelo, 2015), tal como lo es la percepción y la valoración del usuario sobre aspectos relacionados al proceso psicoanalítico que se relacionan con el cambio psíquico, y la narrativa del proceso vivido. Los resultados muestran 4 ejes temáticos con 18 subtemas en total que describen los momentos percibidos como importantes para el cambio psíquico por parte de los usuarios.

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Outcome of Psychoanalytic and Cognitive-Behavioural Long-Term Therapy with Chronically Depressed Patients: A Controlled Trial with Preferential and Randomized Allocation

Abstract: Ré sultat d'une thé rapie psychanalytique et cognitivocomportementale à long terme chez des patients souffrant de dé pression chronique : un essai contrô lé avec allocation pré fé rentielle et randomisé e

Cited by 71 publications

References 43 publications

The Neurobiological Underpinnings of Psychoanalytic Theory and Therapy

The Neurobiological Underpinnings of Psychoanalytic Theory and Therapy

Annual Research Review: Defining and treating pediatric treatment‐resistant depression

Momentos significativos asociados al cambio psíquico

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