Ovarian and Renal Vein Thrombosis: A Rare Cause of Fever Outer the Postpartum Period

Abstract

Although there is no other underlying disease, women can sometimes experience rare and serious diseases such as ovarian vein thrombosis (OVT) and renal vein thrombosis (RVT) after giving birth. The widespread development of thrombosis is treated for the first time in this study. Stasis, coagulation factor abnormalities, and intimal damage to the venous thrombosis risk can increase during pregnancy. It was mentioned that it diagnoses an abnormality in the hypercoagulability half of women with OVT. Despite the hypercoagulant abnormality observed in pregnant women, it was very unusual that the renal vein thrombosis led to this complication. It can lead to severe complication of OVT which can even cause death. It was the first time that the renal vein and ovarian vein thrombosis were observed in the postpartum period, and there was no coagulation abnormality. It is known that the thrombus in the postpartum period can be observed with the fever of unknown origin. The problematic, but rarely observed, postpartum disease such as ovarian venous thrombosis (OVT) is generally observed in the right ovarian vein. In this disease, avoiding the resulting laparotomy heparin and intravenous antibiotics is best solution for the patient. If it is to be noted a fever for unknown reasons, that it be thrombosis.

Ovarian Vein Thrombosis as a Complication of Laparoscopic Surgery

“…OVT is a rare venous thromboembolic disease of puerperium that affects 0.05–0.18% of postpartum women [ 1 ]. The underlying pathophysiology of OVT in pregnancy is attributed to Virchow's triad of venous stasis, endothelial damage, and hypercoagulability [ 2 , 3 ]. Other conditions responsible for causing thrombus formation in ovarian vein are malignancies, pelvic inflammatory diseases, sepsis, and pelvic surgeries.…”

“…It may rarely be idiopathic and occur spontaneously without any identifiable risk factors or underlying hypercoagulable disorders [ 4 , 5 ]. Thrombus occurs in the right ovarian vein in 70–90% of cases, although some authors have reported higher incidence in left ovarian vein as well [ 2 , 6 ]. This increased incidence on right side is due to the longer length and absence of competent valves in right ovarian vein [ 7 ].…”

“…Despite these benefits, many physicians use CT as the first imaging tool due to its easy availability. USG with Doppler may be used for follow-up of OVT patients after the treatment is initiated; its sensitivity in diagnosis of OVT is 52% and is by far poorer than CT or MRA [ 2 , 11 ].…”

“…There are no standard guidelines for the dose, duration, or agent of choice for anticoagulation. Most authors treat their patient for 3–6 months, where therapeutic dose of unfractionated heparin or LMWH (Enoxaparin or Dalteparin) is used for acute treatment and vitamin K antagonist (Warfarin) for maintenance of oral anticoagulation with INR maintained between 2 and 3 [ 1 , 2 , 12 , 13 ]. Rivaroxaban (a heparinoid oral anticoagulant; direct factor Xa inhibitor) has also been proposed as an alternative to vitamin K antagonists for the long-term treatment of OVT [ 14 ].…”

Deep Veins Thrombosis Mimicking an Infection in a Postpartum Woman

“…Exclusion of an infectious aetiology in a postpartum patient with fever was of great importance to us. Fever of unknown origin that persists despite antibiotics is a predictive clue to the formation of thrombus in the postpartum period (Togan et al, 2015). We faced a careful treatment choice challenge successfully and also the matter of which speciality should be responsible for her attendance.…”