Ovarian Yolk Sac Tumor

Abstract

Postsurgery satisfactory AFP decline was an independent significant prognostic factor for patient survival. Omentectomy might not be of therapeutic significance for clinical stage I-II patients.

Is Omentectomy Mandatory Among Early Stage (I, II) Malignant Ovarian Germ Cell Tumor Patients? A Retrospective Study of 223 Cases

“…The 5-year survival rates for patients with and without OMTwere 89.2% and 100%, respectively (P 9 0.05). 3 In this study, we also showed that the 5-and 10-year survival of patients with OMT is not higher than that of patients without OMT (92.4% vs 98.1%, 90.5% vs 98.1%). The results even favor the group without OMT.…”

“…In our previous report about ovarian YST, microscopic omental metastasis is found in only 2.7% patients (1/37) with grossly normal omentum. 3 In the report by Zhao et al 2 on 102 patients with MOGCT and with the disease grossly confined to the ovary, none of the 49 patients who received OMT had microscopic metastasis to the omentum. 2 Second, MOGCT is usually sensitive to chemotherapy, and postoperation chemotherapy is generally planned for MOGCT patients except those with stage IA DSG or IMT.…”

“…2 Previously, our data in 45 patients with stage I or II YST showed that OMT might not improve patient survival. 3 In this study, we aim to further investigate the role of OMT on survival of patients with apparently early stage MOGCT.…”

Are omentectomy and lymphadenectomy necessary in patients with apparently early-stage malignant ovarian germ cell tumors?

“…In the study from Zhao et al regarding malignant ovarian germ cell tumors confined to the ovary, no metastasis was found in 49 patients who underwent omentectomy 12. In our previous study on yolk sac tumor of all stages, metastasis was found in 1 of 37 (2.7%) omentums that appeared normal 14. In the current study, no metastasis was found in the omentums.…”

“…In the study by Mahdi et al, the lymph node metastatic rates for immature teratoma and dysgerminoma were 1.4% (7/516) and 11.3% (40/354), respectively 9. In our previous study on yolk sac tumors, none of the 16 patients with early-stage disease (stage I=12, stage II=4) who underwent lymphadenectomy had lymph node metastasis 14. In the present study, the lymph node metastasis rate was 0.8% (1/119).…”