Oxidative stress in post menopausal women with cardiovascular risk factors

Oxidative stress in elderly population: A prevention screening study

“…These include osteoporosis, in which a key role is played by H 2 O 2 that causes dysfunction in osteoblast activity and reduces the activity of alkaline phosphatase; [52][53][54][55] a reduction in which increased ROS production is highlighted, due to chronic low-intensity inflammation, 56 and cardiovascular disease, where the oxidation of LDL plays a key role; in fact after menopause the risk of coronary heart disease doubles for women as the atherogenic lipids become greater than those of men. 57 Despite that fact that in the present study, as expected, the majority of the senior population is in a condition of OS, surprisingly the levels of peroxides and antioxidants are not linearly correlated with age.…”

“…This phenomenon could be one of the causes of the increased incidence in the female population over 60 of certain diseases in which the role of ROS has been confirmed. These include osteoporosis, in which a key role is played by H 2 O 2 that causes dysfunction in osteoblast activity and reduces the activity of alkaline phosphatase; 52‐55 a reduction in which increased ROS production is highlighted, due to chronic low‐intensity inflammation, 56 and cardiovascular disease, where the oxidation of LDL plays a key role; in fact after menopause the risk of coronary heart disease doubles for women as the atherogenic lipids become greater than those of men 57 …”