Pandemic influenza hospitalization in Spain (2009): Incidence, in-hospital mortality, comorbidities and costs

Serum IgG Concentrations in Adult Patients Experiencing Virus-Induced Severe Asthma Exacerbations

“…Indeed, asthma and obesity have been found as independent risk factors of pandemic influenza hospitalization. 30 In our study, more patients in the positive virus group required intensive care although there was no significant difference. Data from the literature suggest that respiratory viruses may trigger severe asthma exacerbations, particularly in young people.…”

Distinction between rhinovirus‐induced acute asthma and asthma‐augmented influenza infection

“…Several studies have shown that during IFV epidemics, pre‐existing asthma predisposes to hospitalisation . These IFV‐triggered events are frequently considered to be “asthma exacerbations,” but there is little evidence to suggest that this is indeed the case.…”

“…Although several studies have assessed IFV‐induced “asthma attacks” from an epidemiological perspective, few studies have directly focused on the actual clinical presentation of these episodes (and, therefore, whether they could actually be defined as “asthma attacks”) . A recent study in children showed a link between asthma attacks and RV, but not IFV .…”

“…Furthermore, the role of other respiratory viruses in asthma attacks is not as well documented . Influenza (IFV) is one of the most common respiratory pathogens and is associated with considerable morbidity and severe outcomes in patients with asthma …”

The Effect of the 2009 Influenza Pandemic on Absence from Work

“…Excess mortality due to the 2009 pandemic ranged from a low of approximately 0.79 deaths per 100,000 in the United States to a high of 2.7 deaths per 100,000 individuals in Argentina. Prior research has also examined the effects of the 2009 pandemic on health care utilization, including physician visits, visits to emergency departments, and hospitalizations (Jacks et al, 2012;Rodríguez-Rieiro et al, 2012;Rubinson et al, 2013;Schanzer and Schwartz, 2013;Uscher-Pines and Elixhauser, 2006;Weinberger et al, 2012;Yang et al, 2012b); nearly all of these studies find significant increases in health care utilization in the 2009 flu season relative to earlier non-pandemic flu seasons.…”