Paraneoplastic autonomic and sensorimotor neuropathy with dysfunction in the afferent limb of baroreflex arc

Watanabe, Soichi; Shiota, Kunio; Hosokawa, Tsunemichi; Tamura, Nobuki; Kaneko, Akira; Hamaguchi, K; Shimizu, Yasutake; Iwasaki, Akira

doi:10.1016/0165-1838(93)90304-d

Cited by 5 publications

(15 citation statements)

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“…It is considered that damage of the hypothalamus causes SIADH, even if hypothalamic lesions are not detected (24). SIADH has also been documented in patients with peripheral neuropathies such as Guillain-Barré syndrome (25)(26)(27), acute autonomic and sensory neuropathy (28), and paraneoplastic autonomic and sensorymotor neuropathy (29). In previous reports of neuropathies with SIADH, most patients had severe autonomic dysfunction (28,29).…”

Section: Discussionmentioning

confidence: 99%

“…SIADH has also been documented in patients with peripheral neuropathies such as Guillain-Barré syndrome (25)(26)(27), acute autonomic and sensory neuropathy (28), and paraneoplastic autonomic and sensorymotor neuropathy (29). In previous reports of neuropathies with SIADH, most patients had severe autonomic dysfunction (28,29). Although several hypotheses have been proposed to explain these findings, including downward osmotic resetting and enhanced renal tubular sensitivity to ADH (27), the pathogenesis of SIADH in peripheral neuropathy is still not fully understood.…”

Section: Discussionmentioning

confidence: 99%

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Acute Combined Central and Peripheral Demyelination Showing Anti-Aquaporin 4 Antibody Positivity

et al. 2012

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Neuromyelitis optica spectrum disorder (NMOSD) is characterized by optic neuritis or transverse myelitis with anti-aquaporin 4 (AQP4) antibodies (1). We herein present the case of a patient with NMOSD who also was affected with peripheral neuropathy. A 58-year-old woman developed gait disturbance and sensory impairment in the lower limbs. She exhibited longitudinally extensive transverse myelitis with anti-AQP4 antibodies. Nerve conduction studies showed demyelinating changes. Laboratory findings showed hepatitis-C virus (HCV) infection. Her peripheral neuropathy improved after immunotherapy. There have been no previous reports of NMO or NMOSD associated with neuropathy. The HCV infection or undetermined humoral factors other than the anti-AQP4 antibodies may have caused her peripheral neuropathy.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Acute Combined Central and Peripheral Demyelination Showing Anti-Aquaporin 4 Antibody Positivity

et al. 2012

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“…However, the pathogenic mechanism of SIADH in peripheral neuropathy is undetermined. In the previous reports, most of polyneuropathies with SIADH were accompanied by severe autonomic dysfunction (3,4). It is therefore likely that a lesion in the afferent baroregulatory pathway may be one of the causes (4).…”

Section: Discussionmentioning

confidence: 99%

“…Among them are stroke, brain tumor, sinus thrombosis, meningitis, Shy-Drager syndrome and peripheral neuropathy. In regard to peripheral neuropathy, SIADH might be associated with Guillain-Barré syndrome (1, 2), acute autonomic and sensory neuropathy (3), and paraneoplastic autonomic and sensorimotor neuropathy (4).…”

Section: Discussionmentioning

confidence: 99%

Inappropriate Secretion of Antidiuretic Hormone in a Patient with Chronic Inflammatory Demyelinating Polyneuropathy

Taguchi

Sasahara

et al. 2005

Intern. Med.

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“…The syndrome of inappropriate antidiuretic hormone may result from a variety of peripheral neuropathies, such as Guillain-Barré Syndrome (8)(9)(10), chronic inflammatory demyelinating polyneuropathy (11,12) and paraneoplastic neuropathy (13). The mechanism underlying SIADH in these neuropathies is discussed in various ways.…”

Section: Discussionmentioning

confidence: 99%

Syndrome of Inappropriate Antidiuretic Hormone Associated with Eosinophilic Granulomatosis with Polyangiitis

et al. 2016

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A 78-year-old woman with a history of bronchial asthma presented with distal dominant sensory disturbance and weakness in the upper and lower extremities. A biopsy of the left peroneus brevis muscle showed active vasculitis with inflammation extending into muscle fascicles and fibrinoid necrosis of the vessel wall, consistent with eosinophilic granulomatosis with polyangiitis (EGPA). Despite her decreased serum osmolarity, her serum antidiuretic hormone level was not reduced, consistent with the syndrome of inappropriate antidiuretic hormone (SIADH). Intravenous and oral steroid therapy improved her neurological symptoms. Clinicians should consider EGPA as a concurrent, and potentially causative, disorder in cases of SIADH.

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Paraneoplastic autonomic and sensorimotor neuropathy with dysfunction in the afferent limb of baroreflex arc

Cited by 5 publications

References 0 publications

Acute Combined Central and Peripheral Demyelination Showing Anti-Aquaporin 4 Antibody Positivity

Acute Combined Central and Peripheral Demyelination Showing Anti-Aquaporin 4 Antibody Positivity

Inappropriate Secretion of Antidiuretic Hormone in a Patient with Chronic Inflammatory Demyelinating Polyneuropathy

Syndrome of Inappropriate Antidiuretic Hormone Associated with Eosinophilic Granulomatosis with Polyangiitis

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