Parental Smoking During Pregnancy and Its Association with Low Birth Weight, Small for Gestational Age, and Preterm Birth Offspring: A Birth Cohort Study

Ko, Ting-Jung; Tsai, Li-Yi; Chu, Li-Ching; Yeh, Su‐Ling; Leung, Cheung; Chen, Chien-Yi; Chou, Hung-Chieh; Tsao, Po‐Nien; Chen, Pau‐Chung; Hsieh, Wu‐Shiun

doi:10.1016/j.pedneo.2013.05.005

Cited by 250 publications

(200 citation statements)

References 15 publications

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“…Although their prevalence was low, some maternal lifestyle factors, including smoking and alcohol consump tion, are likely to be underreported in the Birth Noti fications data set, relative to previous survey data. 43 There is also potential for residual confounding because of incomplete consideration of some essen tial nutritional elements associated with congenital heart disease, including folic acid and multivitamin supplementation, 8,9 These potential confounders were not available from the data source for this study. We used ICD9CM codes, which are not as specific as the ICD10CM codes; 18 this may have led to some misclassification of disease in both mothers and infants.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

Association of maternal chronic disease with risk of congenital heart disease in offspring

Chou

Chiou

Liang

et al. 2016

CMAJ

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Section: Strengths and Limitationsmentioning

confidence: 99%

Association of maternal chronic disease with risk of congenital heart disease in offspring

Chou

Chiou

Liang

et al. 2016

CMAJ

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“…Cigarette smoke contains mutagenic and carcinogenic agents, 3 as well as toxic agents, which can lead to fetal alterations [23][24][25] such as in the reproductive function stages (folliculogenesis, steroidogenesis, embryo transport, …”

Section: Discussionmentioning

confidence: 99%

Smoking and its association with cryptorchidism in Down syndrome

Duarte

Júnior

Mrad

et al. 2017

Rev. Assoc. Med. Bras.

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Introduction:Cryptorchidism is a common and prevalent condition in patients with Down syndrome. Environmental factors, such as smoking, can be associated with malformations during fetal development. The study of the prevalence of cryptorchidism and its association with parental tobacco use in Down syndrome can contribute to alert health care professionals, patients and family members regarding the prevention of the harms caused by cryptorchidism and its possible predisposing factors. Objective: To evaluate the prevalence of cryptorchidism in Down syndrome and its association with maternal and paternal smoking. Method: Forty (40) patients of a public clinic specialized in Down syndrome were evaluated, using a semi-structured questionnaire for evaluation of antecedents and sociodemographic characteristics, as well as physical and complementary examinations. Results: Cryptorchidism was observed in 27.5% of the patients (95CI 15.98-42.96). Of these, 55% (5/9) were the children of mothers who smoked during pregnancy, and 19.35% (6/31) were the children of mothers who did not smoke during pregnancy (OR = 5.26 [95CI 1.06-25.41]; p=0.032). Similarly, paternal smoking was also observed in greater frequency among the parents of cryptorchid patients compared with subjects with descended testis, 63.36% (7/11) and 31.03% (9/29), respectively (OR = 3.89 .73]; p=0.060). Conclusion:The prevalence of cryptorchidism is high in patients with Down syndrome. We can show a strong association between smoking parents and the occurrence of cryptorchidism, especially when it comes to maternal smoking.

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“…Using Taiwan Birth Cohort to explore the effects of maternal smoking on birth outcomes, Ko et al [7] found that maternal smoking is associated with preterm delivery. The incidences of preterm birth of mothers who smoked during the different pregnancy stages increased with the number of cigarettes smoked daily, which was especially significant among those who smoked more than 20 cigarettes/day.…”

Section: Preterm Birthmentioning

confidence: 99%

Smoking: An Important Environmental Risk Factor in Pregnancy

Qing¹,

Yang²,

Tang³

2018

Pregnancy and Birth Outcomes

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It is generally recognized that smoking has been one of the most public health disorders around the world. Nowadays, more and more studies have proved that smoking during pregnancy is responsible for both maternal and fetal health disorders along with several general health effects. It may lead to various kinds of pregnancy illness and cause risk to the fetus during perinatal stage. After birth, this behavior can also have harmful influences on neonates, and even on children. However, smoking during pregnancy has several adverse effects, the molecular mechanism of it remains unclear. Recently, some studies have proved that it is associated with aberrant epigenetic modifications. All of these remind us that more attention should be paid to maternal cigarette smoking, and more studies should be carried out to confirm the effects and investigate the molecular mechanisms. In this chapter, a brief review is given on the perinatal effects and long-term influences of maternal and passive smoking. We also briefly clarify the epigenetic mechanisms underlying the adverse effects of passive smoking during pregnancy.

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Parental Smoking During Pregnancy and Its Association with Low Birth Weight, Small for Gestational Age, and Preterm Birth Offspring: A Birth Cohort Study

Cited by 250 publications

References 15 publications

Association of maternal chronic disease with risk of congenital heart disease in offspring

Association of maternal chronic disease with risk of congenital heart disease in offspring

Smoking and its association with cryptorchidism in Down syndrome

Smoking: An Important Environmental Risk Factor in Pregnancy

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