Parenteral microemulsions: An overview

Topical Nanoemulgel: A Novel Pathway for Investigating Alopecia

“…Usually, the oil which has maximum solubilising potential for selected drug candidate is selected as an oily phase for the formulation of nanoemulsions. This helps to achieve maximum drug loading in the nanoemulsions [14]. Mixture of oils can also be used to solubilsed the maximum amount of drug [15].…”

A Recent Review on Nasal Microemulsion for Treatment of CNS Disorder

“…Lorazepam (LZM) is a poorly water-soluble drug which can be used as a tranquillizer, muscle relaxant, sleep inducer, sedative and antiepileptic agent [40]. Co-solvent based parenteral formulations, however, have several disadvantages, such as pain and tissue damage at the site of injection and precipitation of the drug on dilution in several cases [41]. Furthermore, parenteral administration of the organic co-solvents can also cause hemolysis [42].…”

Efficacy and mechanism of tanshinone IIA liquid nanoparticles in preventing experimental postoperative peritoneal adhesions in vivo and in vitro

“…22 However, the utility of these approaches is often restricted because of poor stability, complexity associated with manufacturing, and unqualified bioavailability, which makes them unsuitable for large-scale production and clinical application. 23 Liquid NPs have proved an effective vehicle that could increase the bioavailability for many drugs. 24,25 Our previous study has shown that liquid NPs for intravenous administration exhibiting better bioavailability and no systemic toxicity may act as a potential Tan IIA vehicle for clinical application.…”