The paper provides information on the sensitivity of isolates of Mannheimia haemolytica to various antibacterial drugs. It has been established that the high sensitivity of Mannheimia haemolytica is manifested to moxifloxacin, kanamycin, phosphomycin, imipenem, cotrimoxazole, doxycycline, norfloxacin, ciprofloxacin, enrofloxacin, cefazolin and cephalexin, so their use makes it possible to achieve the best therapeutic effect. КЛЮЧЕВЫЕ СЛОВА Манхеймиоз, антибиотикотерапия, лечение, эффективность.