Family planning is an effort to control the birth of children, the ideal space and age for childbirth, pregnancy control, through promotion, protection, and assistance in accordance with reproductive rights to form a quality family. Vasectomy, or vas occlusion, is considered to be the most effective and very popular form of contraception. This study aims to analyze the relationship between knowledge and attitudes with vasectomy participation in men. This study used a cross-sectional approach. The research location is in Madiun City, East Java, Indonesia. The total sample in this study was 323 respondents. The variables in the study were knowledge, attitudes, and participation in vasectomy family planning. There is a relationship between knowledge and attitudes about vasectomy with male participation in vasectomy.