Patient preferences for topical treatment of actinic keratoses: a discrete‐choice experiment

Kopasker, Daniel; Matin, Rubeta; Harwood, Catherine A.; Ismail, Ferina; Lear, John T.; Thomson, J.; Hasan, Zeeshaan‐Ul; Wali, G.N.; Milligan, A; Crawford, Lloyd V.; Ahmed, Ikhlaaq; Duffy, Helen; Proby, Charlotte M.; Allanson, Paul

doi:10.1111/bjd.16801

Cited by 17 publications

(28 citation statements)

References 20 publications

(23 reference statements)

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“…Understanding treatment motivation, expectations, and individual patient preferences critically influence the treatment success. Besides, these factors are important to improve the acceptability of and compliance to treatment regimens [11,12]. Surprisingly, the patient-centered motives and expectations towards AK treatment have received little attention until now but can represent a major barrier for treatment adherence [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial

Steeb

Wessely

Bubnoff

et al. 2020

JCM

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Patient-centered motives and expectations of the treatment of actinic keratoses (AK) have received little attention until now. Hence, we aimed to profile and cluster treatment motivations and expectations among patients with AK in a nationwide multicenter, cross-sectional study including patients from 14 German skin cancer centers. Patients were asked to complete a self-administered questionnaire. Treatment motives and expectations towards AK management were measured on a visual analogue scale from 1–10. Specific patient profiles were investigated with subgroup and correlation analysis. Overall, 403 patients were included. The highest motivation values were obtained for the items “avoid transition to invasive squamous cell carcinoma” (mean ± standard deviation; 8.98 ± 1.46), “AK are considered precancerous lesions” (8.72 ± 1.34) and “treating physician recommends treatment” (8.10 ± 2.37; p < 0.0001). The highest expectation values were observed for the items “effective lesion clearance” (8.36 ± 1.99), “safety” (8.20 ± 2.03) and “treatment-related costs are covered by health insurance” (8.00 ± 2.41; p < 0.0001). Patients aged ≥77 years and those with ≥7 lesions were identified at high risk of not undergoing any treatment due to intrinsic and extrinsic motivation deficits. Heat mapping of correlation analysis revealed four clusters with distinct motivation and expectation profiles. This study provides a patient-based heuristic tool for a personalized treatment decision in patients with AK.

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Section: Introductionmentioning

confidence: 99%

Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial

Steeb

Wessely

Bubnoff

et al. 2020

JCM

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“…Other studies have analyzed the willingness of consumers to participate in experimental clinical treatments aiming to identify treatment preferences for specific conditions through a couple of approaches: (1) Investigate the availability of patients or consumers that would use treatments to prevent or reduce the incidence of skin diseases such as psoriasis and actinic keratosis, considering attributes and efficacy levels (percentage of improvement in skin appearance and reduction of skin cancer risk), intensity, duration, and severity of secondary reactions Kopasker et al [15]; (2) analyze the commercial availability of cosmetic treatments with different attributes, including the function (restore wrinkled skin, reduce pore size, treat acne dots and spots, skin moisturizer), presentation (ointment, cream, lotion), packaging (pump-style, tube, jar, ampoule), and price [16].…”

Section: Literature Reviewmentioning

confidence: 99%

Consumer Preferences for Labeled Plant-Based Products Associated with Traditional Knowledge: A Study in Protected Natural Areas of Northwest Mexico

Avilés-Polanco¹,

Almendarez-Hernández²,

Beltrán-Morales³

et al. 2021

Land

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The use of plants associated with traditional knowledge by pharmaceutical, cosmetic, agro-food, and biotechnology industries represents a potential source of benefits for indigenous groups and local communities within the access and benefit-sharing mechanisms established in the Nagoya Protocol. We used a consumer-choice experiment to evaluate consumer preferences concerning a cosmetic product with attributes related to the traditional knowledge of local plants (efficacy, price, and information). The results indicate that consumers experience higher wellness levels by consuming a cosmetic product with an information label associated with a plant of traditional use. A rise in consumer income increases the likelihood of consuming products with traditional-knowledge attributes. Higher prices are associated with a lower probability of purchase. The random coefficient reveals mixed preferences related to product efficacy level. This work shows the potential demand, by high-income consumers, of cosmetic products labeled with formulation information based on traditional knowledge associated with local plants growing in Protected Natural Areas of northwest Mexico.

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“…Indeed, physicians should also take into account the therapeutic burden for these predominantly elderly patients; acceptability and adherence to treatments should be taken into consideration. As such, patients may reject an AK treatment if the perceived value of the therapeutic benefit is outweighed by the subjective costs associated with the medical burden . Therefore, it is important to inform each individual patient about the effects and side‐effects of the various treatment options and make an evidence‐based, shared decision.…”

mentioning

confidence: 99%

Innovative devices for actinic keratoses: a hot‐button issue

Samimi

Kelleners‐Smeets

2020

Br J Dermatol

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Patient preferences for topical treatment of actinic keratoses: a discrete‐choice experiment

Abstract: Evidence of significant variation in the perceived utility of treatments across patients highlights the importance of taking individual patient preferences into account to improve AK treatment acceptability and adherence.

Cited by 17 publications

References 20 publications

Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial

Treatment Motivations and Expectations in Patients with Actinic Keratosis: A German-Wide Multicenter, Cross-Sectional Trial

Consumer Preferences for Labeled Plant-Based Products Associated with Traditional Knowledge: A Study in Protected Natural Areas of Northwest Mexico

Innovative devices for actinic keratoses: a hot‐button issue

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