2002
DOI: 10.1006/nimg.2002.1197
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Patterns of Cerebral Atrophy in Dementia with Lewy Bodies Using Voxel-Based Morphometry

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Cited by 186 publications
(91 citation statements)
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References 42 publications
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“…Using both VBM and ROI analysis they studied subjects with DLB (n = 72), AD (n = 72) and controls (n = 72) with careful matching for age, education and dementia severity. They found very little cortical grey matter loss, in contrast to the relatively diffuse pattern of grey matter loss observed by others [7,9,10] . However, they report scattered regions of cortical loss in frontal and parietal lobes which is in keeping with other studies, but to a lesser degree.…”
Section: Cortical Atrophymentioning
confidence: 44%
See 1 more Smart Citation
“…Using both VBM and ROI analysis they studied subjects with DLB (n = 72), AD (n = 72) and controls (n = 72) with careful matching for age, education and dementia severity. They found very little cortical grey matter loss, in contrast to the relatively diffuse pattern of grey matter loss observed by others [7,9,10] . However, they report scattered regions of cortical loss in frontal and parietal lobes which is in keeping with other studies, but to a lesser degree.…”
Section: Cortical Atrophymentioning
confidence: 44%
“…A common finding in structural MR studies in dementia is whole brain atrophy when compared with control subjects with widespread grey matter reduction in the frontal, temporal and parietal areas [6][7][8][9] .…”
Section: Cortical Atrophymentioning
confidence: 99%
“…In this study, both standard and optimized VBM [12,13] methods were performed. For standard VBM, the images were automatically segmented into gray matter (GM), white matter (WM) and CSF images using a cluster analysis technique.…”
Section: Discussionmentioning
confidence: 99%
“…A characteristic pattern of atrophy has been identified in AD, with marked atrophy of the hippocampus and medial temporal lobe [63] . Among the few MRI studies involving patients with DLB, significant differences have been reported between DLB and AD; the typical finding is preservation of the hippocampus and medial temporal lobe volume in DLB in comparison with AD [64][65][66] . These differences are based on group studies and cannot reliably distinguish DLB from AD on an individual level, demonstrated by the low reported sensitivity (40%) [65] .…”
Section: Imaging Techniquesmentioning
confidence: 99%