Patterns of prescription of hypoglycaemic drugs in Gran Canaria (Canary Islands, Spain) and estimation of the prevalence of diabetes mellitus

Pablos-Velasco, Pedro de; Martínez-Martín, Francisco Javier; Molero, Rubén; Rodríguez-Pérez, Fátima; Garcia-Puente, I.; Caballero, A

doi:10.1016/s1262-3636(07)70216-1

Cited by 18 publications

(16 citation statements)

References 17 publications

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“…Insulin was prescribed for 11·5% of the type 2 diabetic patients. This is higher than the 8% reported in Canada (33) and 9·4% in Spain (34) but less than the 20% reported in Sweden (35) and 23% in Denmark (36).…”

Section: Discussioncontrasting

confidence: 55%

Drug utilization of oral hypoglycemic agents in a university teaching hospital in India

Sultana

Kapur²,

Aqil

et al. 2010

Journal of Clinical Pharmacy and Therapeutics

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This study strongly highlights the need for patient education or counselling on use of antidiabetic and concomitant drugs, monitoring of blood glucose and glycosylated haemoglobin (HbA1c) levels, diet control, and correction of diabetic complications. Metabolic control was poor and HbA1c monitoring was underutilized. Clinical monitoring of patients' adherence to prescribed treatments is recommended and measures should be taken to improve it.

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Section: Discussioncontrasting

confidence: 55%

Drug utilization of oral hypoglycemic agents in a university teaching hospital in India

Sultana

Kapur²,

Aqil

et al. 2010

Journal of Clinical Pharmacy and Therapeutics

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“…The mean duration of DM is 6.44±5.49 years. A study from Spain reported the mean duration of diabetes as 11.8±8 years [14]. The comparatively lower duration of DM in our study may be due to lack of early diagnosis, as many of the freshly detected cases were suffering from the disease for a long time without being aware of it.…”

Section: Discussioncontrasting

confidence: 55%

Drug utilization study in diabetic patients attending medicine outpatient department of a tertiary care hospital

Suthar

Dholaria

Chavda

et al. 2014

Int J Diabetes Dev Ctries

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A cross-sectional observational study of 6 months duration was done in a tertiary care hospital to determine the drug utilization pattern among diabetic outpatients. We analyzed the collected data by using descriptive statistics and determined drug use indicators, defined daily dose (DDD)/ 1000 inhabitants/day and utilization pattern of antidiabetic drug. Antidiabetic drugs were classified according to Anatomical Therapeutic Chemical (ATC) classification and their consumption was measured in terms of DDD/1000 inhabitants/day. 625 prescriptions were collected during this study. Type 2 diabetes mellitus (T2DM) constituted the most predominant (95.36 %) group of patients; hence oral antidiabeticdrugs were prescribed to a major extent. The average number of drugs per encounter was 4.18 and the average drug cost per encounter was 269.04 Indian National Rupees (INR). Majority of the patients (77.44 %) were receiving three or more drugs. Monotherapy was observed in 29.6 % of patients with insulin as the most predominant concurrently prescribed drug (13.28 %). Dual therapy was prescribed to 45.44 % patients with metformin and glibenclamide (25.44 %) being the predominant combination. Among the various insulin regimens, typical split-mixed regimen (77.18 %) was the most frequently prescribed regime. Our results suggest that there still remains a scope for improving the prescribing pattern of antidiabetic drugs. The favoured use of metformin is acceptable, but the preference of glibenclamide over other sulfonylureas is unsound.

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“…[1] Most of our patients had a history of diabetes around 5-15 years which an earlier study also reported. [21]…”

Section: Discussionmentioning

confidence: 99%

Evaluation of antidiabetic prescriptions, cost and adherence to treatment guidelines: A prospective, cross-sectional study at a tertiary care teaching hospital

Acharya

Shah

Solanki

et al. 2013

J Basic Clin Pharma

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Introduction:Diabetes mellitus is on alarming rise in India. Drug utilization studies help to identify the adherence to standard treatment guidelines and to evaluate the rational drug usage.Objective:To study prescription pattern, calculate the cost of antidiabetic drugs and to evaluate the adherence to treatment guidelines in diabetic patients attending the medicine outpatient department in a tertiary care teaching hospital.Materials and Methods:A prospective observational study was carried out for a period of 5 months. The diabetic patients who visited the medicine outdoor department were included. Demographic data and complete prescription details were recorded in the structured case record form. Cost of the drug therapy was calculated from the patient's bills. Indian Council for Medical research guidelines-2005 for diabetes management was used to evaluate the adherence.Results:A total of 250 patients were enrolled in the study with mean age 57.91 ± 9.37. Out of 250 patients 126 (50.4%) were male and rest were female. A total of 1,391 drugs were prescribed, with mean of 5.56 ± 2.52 drugs and out of which 539 drugs were antidiabetics with mean of 2.18 ± 0.96. In monotherapy, metformin was frequently 218 (40.45%) prescribed. Glimepiride and metformin was the most frequently prescribed in 119 (76.28%) out of 156 antidiabetic drug combinations. Most commonly used drugs other than antidiabetics were aspirin 146 (18.9%) and atorvastatin 119 (15.41%). Mean cost of therapy for a month for a diabetic patient was 354.60 ± 305.72 INR. Majority 209 (83.6%) of prescriptions was in accordance to guidelines.Conclusion:Metformin was the most frequently prescribed drug in the diabetes patient. Metformin and glimeperide being the most frequent combination used. Majority of the prescriptions followed standard guidelines.

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Patterns of prescription of hypoglycaemic drugs in Gran Canaria (Canary Islands, Spain) and estimation of the prevalence of diabetes mellitus

Cited by 18 publications

References 17 publications

Drug utilization of oral hypoglycemic agents in a university teaching hospital in India

Drug utilization of oral hypoglycemic agents in a university teaching hospital in India

Drug utilization study in diabetic patients attending medicine outpatient department of a tertiary care hospital

Evaluation of antidiabetic prescriptions, cost and adherence to treatment guidelines: A prospective, cross-sectional study at a tertiary care teaching hospital

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