PCR Quantification of D. folliculorum in Periocular Basal Cell Carcinoma

et al. 2022

Preprint

Aim: To determine the prevalence and influencing factors of Demodex folliculorum (DF) in the eyelashes of healthy young males. Methods: An epidemiological cross-sectional prevalence study was conducted. A total of 2253 healthy young males (aged 17-24 years) were studied for the presence of DF within eyelash follicles. The presence of DF was analyzed according to various factors. Results: The total prevalence of DF was 20.73% in our study. Subjects with history of myopia correction surgery had a statistically significant increase in the positive rate of DF (P<0.001). The positive rate was higher in subjects with ocular symptoms than in those without symptoms (P<0.05). Factors such as the educational level, long-term residence, annual household income, sleep time, time of using electronic products, smoke and drinking habits, had no significant correlation with the DF positive rate (all P>0.05). According to the multivariate logistic regression analysis, the history of myopic correction surgery was the risk factors of DF infection (P<0.001). There was no correlation between ocular discomfort and DF infection (P>0.05). Conclusions: The prevalence of DF in eyelash follicles in healthy young men was relatively high. The history of myopic correction surgery was an important risk factor for the infection.

Section: Introductionmentioning

confidence: 99%

The Prevalence of Ocular Demodex folliculorum in 2253 Young Males

et al. 2022

Preprint

“…Demodex brevis resides solitarily in the meibomian and sebaceous glands around the eyelash follicles 5 . A growing body of evidences indicate that DF plays an important role in the onset of many ocular surface diseases, such as blepharitis 6 , allergic conjunctivitis 7 , pterygium 8 , chalazia 9 , and periocular basal cell carcinoma 10 . Misdiagnosis of DF infection during these diseases might lead to failure of treatment, relapse and even serious complications 11 .…”

Section: Introductionmentioning

confidence: 99%

The prevalence of ocular Demodex folliculorum in 2253 young males

et al. 2022

Sci Rep

To investigate the prevalence and influencing factors of Demodex folliculorum (DF) in the eyelashes of healthy young males. An epidemiological cross-sectional prevalence study was conducted. We conducted visual acuity, eye-related examination, eyelash microscopic examination and DF count of recruits in Fujian Province in 2019. The presence of DF was analyzed according to age, keratorefractive surgery, annual household income, educational level, long-term residence, sleep time, time of using electronic products, smoking and drinking habit. A total of 2253 healthy young males (aged 17–24 years) were studied for the presence of DF within eyelash follicles. The total prevalence of DF was 20.73% in our study. Subjects with history of keratorefractive surgery had a statistically significant increase in the prevalence of DF (P < 0.001). The prevalence of DF was higher in subjects with ocular symptoms than in those without symptoms (P < 0.05). Factors such as the educational level and so on we analyzed had no significant correlation with the prevalence of DF (all P > 0.05). According to the multivariate logistic regression analysis, the history of keratorefractive surgery was the risk factors of DF infection (P < 0.001), and the risk of infection was 1.437 times higher in the population with the history of keratorefractive surgery than in the population without. There was no correlation between ocular discomfort and DF infection (P > 0.05). The prevalence of DF in eyelash follicles in healthy young males was relatively high. The history of keratorefractive surgery was an important risk factor for the infection.

Section: Introductionmentioning

confidence: 99%

The Prevalence of Ocular Demodex folliculorum in 2253 Young Males The Prevalence of Ocular Demodex folliculorum

et al. 2021

Preprint

AimTo determine the prevalence and influencing factors of Demodex folliculorum (DF) in the eyelashes of healthy young males.MethodsAn epidemiological cross-sectional prevalence study was conducted. A total of 2253 healthy young males (aged 17-24 years) were studied for the presence of DF within eyelash follicles. The presence of DF was analyzed according to various factors.ResultsThe total prevalence of DF was 20.73% in our study. Subjects with history of myopia correction surgery had a statistically significant increase in the positive rate of DF (P<0.001). The positive rate was higher in subjects with ocular symptoms than in those without symptoms (P<0.05). Factors such as the educational level, long-term residence, annual household income, sleep time, time of using electronic products, smoke and drinking habits, had no significant correlation with the DF positive rate (all P>0.05). According to the multivariate logistic regression analysis, the history of myopic correction surgery was the risk factors of DF infection (P<0.001). There was no correlation between ocular discomfort and DF infection (P>0.05).ConclusionsThe prevalence of DF in eyelash follicles in healthy young men was relatively high. The history of myopic correction surgery was an important risk factor for the infection.