2021
DOI: 10.1016/j.spen.2021.100927
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Pediatric Intracranial Hypotension and Post-Dural Puncture Headache

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Cited by 7 publications
(5 citation statements)
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“… 27 In addition, the reduction in CSF volume caused by CSF outflow leads to a reduction in intracranial pressure. 38 , 39 , 40 , 41 This reduction affects CSF circulation and reduces CSF turnover, 42 thereby limiting Tau drainage from the central to peripheral circulatory system, resulting in the accumulation of Tau in the CSF. 25 The interplay of these two factors is necessary for Tau accumulation in the CSF.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“… 27 In addition, the reduction in CSF volume caused by CSF outflow leads to a reduction in intracranial pressure. 38 , 39 , 40 , 41 This reduction affects CSF circulation and reduces CSF turnover, 42 thereby limiting Tau drainage from the central to peripheral circulatory system, resulting in the accumulation of Tau in the CSF. 25 The interplay of these two factors is necessary for Tau accumulation in the CSF.…”
Section: Discussionmentioning
confidence: 99%
“…No. KHB3481) and Amyloid-beta 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 (Thermo Fisher, Cat. No.…”
Section: Methodsunclassified
“…Newer studies now show that the actual success of EBP in adults is between 33% and 91% [2]. In pediatric patients, the incidence of sustained success even with a large single-volume blood patch is around 30-70% [5].…”
Section: Discussionmentioning
confidence: 99%
“…In contrast to adults, an EBP in children usually necessitates sedation or general anesthesia because children generally have a fear of needles. However, an EBP does not guarantee the resolution of the PDPH, and the updated success rate of an EBP in pediatrics may be as low as 72% [ 5 ]. To improve our understanding of PDPH and its treatment in children, we present a case report of a refractory PDPH that was initially treated with conservative and medical management and multiple EBPs that finally resolved with a sphenopalatine ganglion (SPG) nerve block [ 6 , 7 ] using a J-tip style catheter instead of the traditional cotton swab.…”
Section: Introductionmentioning
confidence: 99%
“…Despite its advantages, spinal anesthesia is not without potential complications. Some complications associated with spinal anesthesia include post-dural puncture headache (PDPH), hypotension, urinary retention, infection, bleeding, and nerve injury (Peterson et al, 2021). PDPH is one of the most common complications of spinal anesthesia.…”
Section: Introductionmentioning
confidence: 99%