Pediatric lipoblastoma in the head and neck: A systematic review of 48 reported cases

Pham, Nguyen; Poirier, Brian; Fuller, Scott C.; Dublin, Arthur B.; Tollefson, Travis Tate

doi:10.1016/j.ijporl.2010.04.010

Cited by 58 publications

(55 citation statements)

References 28 publications

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“…The lesion contents typically appear heterogeneously fatty, with intermediate streaks and whorls of higher signal intensity attributable to the intralesional fibrous tissue framework. Unlike subcutaneous fat deposits, lipoblastomas exhibit high signal intensity on fat-suppressed images, a diagnostically specific characteristic (27,30). The imaging features of lipoblastoma overlap with those of well-differentiated liposarcoma (see the section on "Atypical Lipomatous Tumor [Well-differentiated Liposarcoma]"); however, patient age allows reliable differentiation of the two entities (3).…”

Section: Lipoblastomamentioning

confidence: 99%

Soft Tissue Tumors of the Head and Neck: Imaging-based Review of the WHO Classification

Razek

Huang²

2011

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The World Health Organization (WHO) system for defining and classifying soft tissue tumors is usually applied to lesions that occur in the trunk and extremities, but it also provides an excellent framework for characterizing nonepithelial extraskeletal tumors of the head and neck. Although nonepithelial extraskeletal tumors are in the minority among head and neck lesions, they are by no means rare. The WHO classification system recognizes nine major types based on histologic differentiation: adipocytic, fibroblastic or myofibroblastic, fibrohistiocytic, smooth muscle, skeletal muscle, vascular, pericytic, and chondro-osseous tumors, as well as soft tissue tumors of uncertain differentiation. Tumors of each histologic type may be further subclassified on the basis of their biologic behavior as benign, intermediate (ie, having malignant potential), or malignant. Imaging plays an important role in the noninvasive diagnosis and characterization of nonepithelial soft tissue tumors of the head and neck, providing clues about tumor grade, composition, extent, and involvement of adjacent structures. Although the imaging characteristics of many such tumors are nonspecific, consideration of the clinical history in concert with the imaging findings may help limit the differential diagnosis or even allow reliable diagnosis of some of these tumors.

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Section: Lipoblastomamentioning

confidence: 99%

Soft Tissue Tumors of the Head and Neck: Imaging-based Review of the WHO Classification

Razek

Huang²

2011

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129

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“…Recurrence rates of between 14% and 27% have been cited. 7,8 Mognato et al, 9 reported a case of spontaneous resolution of lipoblastomatosis after incisional biopsy.…”

Section: Discussionmentioning

confidence: 99%

Rapidly-growing buccal mass in a 6-month-old infant

Kumar

Brierley

Hunter

et al. 2015

British Journal of Oral and Maxillofacial Surgery

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“…While they most commonly appear in the trunk and extremities, they can present anywhere in the body. They are believed to have a 27% local recurrence rate with curative surgical excision as the primary mainstay of treatment 1. They have not been found to metastasise and only become symptomatic with mass effect on adjacent structures.…”

Section: Descriptionmentioning

confidence: 99%