Peer Reviewed: Microfluidics: Controlling Fluids in Small Places

Peer Reviewed: Shear-Driven Flow Approaches to LC and Macromolecular Separations

“…The injection process also must occur swiftly enough to prevent noninjected sample from leaking into the channel. In CE-and CEC-on-a-chip, the injection problem has occupied many researchers, who have had to make numerous adaptations to finally reach a suitable solution (17)(18)(19).…”

Development of Fast HPLC Methods

“…More recently, polymeric substrates such as poly(dimethylsiloxane) (PDMS) or poly(methyl methacrylate) (PMMA) have been used [46,47]. The channel dimensions range from tens of micrometers in width and depth to less than a micrometer.…”

“…The miniaturization and integration of other components, such as pumps, valves, and detection schemes, onto the chip is another essential step for future development. The reader is referred to the reviews cited in the references for research performed with microchips [46][47][48].…”

Flow of Multiple Fluids in a Small Dimension

“…As a result, manipulating fluid flows in microdevices is a topic of great interest, primarily centered on driving liquids through narrow (~<100-µm) channels etched on a planar surface (1).…”