PEGylated PLGA nanoparticles as protein carriers: synthesis, preparation and biodistribution in rats

PEGylation of magnetic poly(glycidyl methacrylate) microparticles for microfluidic bioassays

“…The difference in ZP before and after PEG-coating reached 13 mV in KCl and 14 mV in phosphate buffer, which is probably caused by the presence of a methoxy group at the end of the PEG. The results correspond with those in previously published reports 49,50 and proved that PEG was present on the microspheres. In addition to ZP, pI values of both neat and PEGylated PGMA microspheres were determined.…”

Impact of PEG and PEG- b -PAGE modified PLGA on nanoparticle formation, protein loading and release

“…For all PLGA polymers an average load of 8.2 ± 1.0%, independent of the Mn PLGA , lactic:glycolic acid ratio and particle size was found. however this was not significant -an observation which has already been described in literature (Li et al, 2001;Tobío et al, 1998).…”

“…From these loading studies, we conclude that the PEG-block in the PEGylated PLGAs has no significant influence on protein encapsulation, in contrast to the insertion of the PAGE building block which is determined to have a significant impact (Li et al, 2001;Tobío et al, 1998).…”

PLGA-Based Nanoparticles as Cancer Drug Delivery Systems

“…Hydrophilic polymers can be useful at the surface of NPs by adsorption of surfactants or by utilize of block copolymers or branched copolymers (Stolnik et al, 1995;Storm et al, 1995;Torchilin and Trubetskoy, 1995;Mahapatro and Singh, 2011). Surface chemistry Analysis is determined by X-ray photoelectron spectroscopy (Mu and Feng, 2003;Si-Shen et al, 2004;Kim et al, 2005), Fourier transform infrared spectroscopy (Li et al, 2001;Choi and Kim, 2007;Yang et al, 2007) and Nuclear magnetic resonance spectroscopy (Li et al, 2001;Avgoustakis et al, 2002;Cheng et al, 2007;Dinarvand et al, 2011).…”