Pembelajaran jarak jauh membuat beberapa aktivitas belajar siswa terhambat. Penelitian ini bertujuan untuk mengembangkan website berbasis keterampilan proses sains interaktif untuk siswa kelas X Animalia. Metode penelitian dan pengembangan dengan model ADDIE (Analyze, Design, Develop, Implement, and Evaluate) digunakan dalam penelitian ini. Pengumpulan data dilakukan dengan validasi website dari pakar, tanggapan siswa dan guru, dan hasil kegiatan ilmiah siswa. Hasil validitas website sebesar 95%, 88%, dan 89% dengan kategori sangat valid. Respon siswa dan beberapa keterampilan proses sains mereka juga bagus, berdasarkan analisis model Rasch. Selain itu, umpan balik guru baik dengan beberapa saran. Website ini dapat menjadi solusi yang baik untuk mengajarkan keterampilan pengelompokan, penerapan konsep, dan interpretasi data.Interactive website development based on science process skills on animalia for 10th grader. Distance learning makes some of student's learning activity hampered. This research aims to develop interactive science process skills-based website for tenth grader on Animalia. Research and development method with ADDIE (Analyze, Design, Develop, Implement, and Evaluate) model is used in this study. The data was collected by website's validation from the experts, students and teacher's responses, and students' scientific activity results. The results of website's validity amounted to 95%, 88%, and 89% with a very valid category. Students' responses and some of their science process skills are also great, based on Rasch model analysis. Besides, teacher's feedback is good with some suggestion. This website can be a good solution to teach grouping, concept applying, and data interpretating skills.