Penile ischaemia secondary to COVID‐19: why should the dermatologist be concerned?

Sarkis, Pierre; Sarkis, Julien; Alkassis, Marwan; Assaf, Joy; Gharib, Khalil El

doi:10.1111/jdv.17287

Cited by 7 publications

(9 citation statements)

References 10 publications

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“…In one of our patients, necrosis of the penis was detected along with finger necrosis. To the best of our knowledge, this is the second covid‐19 related penile necrosis case in the literature after the publication of Sarkis et al 22 …”

Section: Discussionmentioning

confidence: 79%

“…In one of our patients, necrosis of the penis was detected along with finger necrosis. To the best of our knowledge, this is the second covid-19 related penile necrosis case in the literature after the publication of Sarkis et al 22 It is reported that necrotic lesions are more common in the distal leg areas where hydrostatic pressure is high. 23 In two of our patients who had skin necrosis, necrosis was in the distal of the leg in line with literature.…”

Section: A S Ementioning

confidence: 73%

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Acro‐ischemic lesions in COVID‐19 patients: A case series

Ozbey

Algan

2022

J of Cosmetic Dermatology

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COVID-19 is a systemic disease characterized by vascular damage, increased inflammation, and hypercoagulability. Acral ischemic lesions occur as a result of increased inflammation and cutaneous thrombosis. Skin lesions can sometimes be the only symptom of COVID-19. In this respect, recognizing acro-ischemic lesions, which are skin lesions, may help in the early diagnosis of the disease and in predicting the prognosis. In patients with skin lesions without typical symptoms, the diagnosis of COVID-19 should be kept in mind. Herein, we describe five patients affected by COVID-19 which developed acro-ischemic lesions.

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Section: Discussionmentioning

confidence: 79%

Section: A S Ementioning

confidence: 73%

Acro‐ischemic lesions in COVID‐19 patients: A case series

Ozbey

Algan

2022

J of Cosmetic Dermatology

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“…In the end, we found only one publication by Sarkis et al that presented the penile ischemic condition in COVID-19 infection. 5 This publication reported glans penile discoloration due to ischemia secondary to COVID-19. However, the patient had several comorbidities such as type 2 diabetes, hypertension, and end-stage kidney disease which could also be risk factors for thrombus vasculopathy.…”

Section: Discussionmentioning

confidence: 97%

“…3,4 Recently, other serious clinical manifestations associated with genitalia condition were reported in patients with SARS-CoV-2 infection with penile ischemia. 5 In patients infected by SARS-CoV-2, penile priapism has also been reported. 6,7 Some authors have speculated that these conditions related to COVID-19 may be due to severe hypercoagulability and thrombotic tendency observed in patients with COVID-19.…”

Section: Introductionmentioning

confidence: 99%

“…6,7 Some authors have speculated that these conditions related to COVID-19 may be due to severe hypercoagulability and thrombotic tendency observed in patients with COVID-19. 5,8 On the other hand, penile involvement in leprosy is uncommon. 9 Leprosy (also known as Hansen's disease) is an infection caused by Mycobacterium leprae (M. leprae) that can damage the peripheral nerves and bone absorption.…”

Section: Introductionmentioning

confidence: 99%

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Case Report: Glans penile necrosis in a patient with SARS-CoV-2 and leprosy infection

2022

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Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was firstly identified in China and has been declared a global pandemic. Several serious extrapulmonary manifestations due to SARS-CoV-2 infection have also been reported and associated with hypercoagulability thrombotic vasculopathy. In addition, cases of Mycobacterium-leprae infection have also been known associated with blood coagulation abnormality. Methods: Here, we report a 56-year-old male with coronavirus disease-19 (COVID-19) with concomitant leprosy infection with manifestation of glans penile necrosis, presented to the emergency department with acute penile pain. This case is unique because no occlusion blood flow to the penile was observed in the radiographic imaging. We described the potential pathophysiology in this case through a literature review. Results: The patient received treatment according to the COVID-19 protocol and was given low molecular weight heparin (LMWH) therapy for 4 days. During the follow up, the clinical and functional condition of the penis showed significant improvement. Conclusions: Microthrombus involvement, platelet abnormalities and impaired hemostasis due to SARS-CoV-2 and leprosy co-infection are the hypothesis in this case report.

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