Penurunan Kadar Gula Darah Akibat Pemberian Ekstrak Manggis (&lt;i&gt;Garcinia mangostana&lt;/i&gt;) dan Tomat (&lt;i&gt;Lycopersicum esculentum Mill&lt;/i&gt;) pada Tikus Diabetes

Yusni, Yusni; Akbar, Ieva Baniasih; Rezania, Rezania; Fahlevi, Raipati

doi:10.29313/gmhc.v5i1.2097

Cited by 4 publications

(5 citation statements)

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“…Research conducted by Astuti and R (2018) revealed that provision of tomato juice to blood glucose levels in pre-diabetes as much as 200 ml for 21 days showed a decrease in blood glucose by 9.00 mg/dl 2 . Another research conducted by Yusni (2015) showed that the administration of tomato extract and mangosteen extract to diabetic mice each 50 mg/kg bb/day for seven days showed a decrease in blood glucose levels by 56.67% 7 . Research by Chairunnisa (2012) was conducted by giving tomato paste to diabetic mice as much as 62 mg for 7 days reduced blood glucose levels by 262 mg/dl with a decreasing percentage reaching 75.60% 8 .…”

Section: Discussionmentioning

confidence: 98%

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Effect of tomato and red guava juice on blood glucose level in overweight woman

Izzati

Jaelani

Setiadi

et al. 2021

JGI

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Background: Based on the results of Riskesdas 2018 that the prevalence of diabetes mellitus in Indonesia showed an increase from 6.9% to 8.5%. Overweight is closely related to impaired blood glucose, insulin resistance, and decreased insulin secretion. Preventive efforts that have been made using non-pharmacological treatments, such as increasing the intake of fiber and lycopene from fruits.Objectives: This study aimed to determine the effect of tomato juice and guava juice on blood glucose levels in overweight women.Materials and Methods: The study design is a true experiment conducted in 11subjects in treatment group and 11 subjects in control group. The subject of this study were overweight adult women 45-55 years. Blood sampling was taken in the morning, then glucose levels were measured using the GOD-PAP method (Glucose Para Amino Phenazone). We gave 600 ml of tomato juice and red guava every day for 21 days. To find the effect of juice on fasting blood glucose levels controlled by nutrient intake and physical exercise using the Repeated Measure ANOVA test.Results: In the treatment group, there was a decrease of 3.24 mg/dl in blood glucose levels; while, in the control group, the decrease in blood glucose levels was only 0.26 mg/dl. However, we found no statistically significant differences in both groups.Conclusions: Consumption of tomato juice and red guava reduced fasting blood glucose.

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Section: Discussionmentioning

confidence: 98%

“…Lycopene binds to reactive oxygen and increases antioxidant potency, thereby reducing oxidative damage to lipids. Meanwhile, the non-oxidative mechanism of lycopene is done through gene function which improves gap-junction communication, hormone modulation, and immune response, all of which can reduce degenerative diseases such as DM 7 .…”

Section: Discussionmentioning

confidence: 99%

Effect of tomato and red guava juice on blood glucose level in overweight woman

Izzati

Jaelani

Setiadi

et al. 2021

JGI

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“…A decrease follows this damage in insulin secretion, which results in the reaction of glycogenesis and reduced glucose transport in cells. In addition, glycogenolysis becomes uncontrolled, resulting in increased blood glucose in the body (Yusni et al 2017). Meanwhile, according to Sari et al (2020), alloxan is a toxic glucose analog that selectively destroys insulinproducing pancreatic cells.…”

Section: Discussionmentioning

confidence: 99%

Effect of palm sap (Arenga pinnata) on blood glucose levels of mice (Mus musculus) alloxan-induced diabetic

LIPUTO

Lamondo

SOLANG

2022

Asian J Nat Prod Biochem

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Abstract. Liputo SM, Lamondo D, Solang M. 2021. Effect of palm sap (Arenga pinnata) on blood glucose levels of mice (Mus musculus) alloxan-induced diabetic. Asian J Nat Prod Biochem 20: 11-15. This study aims to determine the effect of palm sap (Arenga pinnata (Wurmb) Merr.) in reducing blood glucose levels in alloxan-induced diabetic mice (Mus musculus Linnaeus, 1758). Twenty-five mice aged 2-3 months were grouped into a negative control group, a positive control group and a palm sap group (0.2 mL, 0.4 mL, and 0.6 mL). The result showed that the palm sap with a dose of 0.4 mL was the most significant in reducing blood glucose levels. This study concluded that the administration of palm sap affected decreasing blood glucose levels (p <0.05).

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“…(Wulandari, 2014) menyatakan hasil penelitiannya bahwa rata-rata kadar gula darah sebelum mengkonsumsi jus kulit buah manggis 210,9 mg/dl dan rata- rata setelah mengkonsumsi jus buah manggis sebesar 169,9 mg/dl. (Yusni, Akbar, Rezania, & Fahlevi, 2017) menyatakan bahwa pemberian ekstrak kulit manggis dan tomat dengan dosis 50mg/kg BB/hari masingmasing menurunkan kadar glukosa darah bagi diabetes. (Kurniawati, 2014) menyatakan bahwa xanton dalam jus kulit buah manggis dapat menghambat aktivitas enzim glukosidae sebesar 64,71% pada penderita diabetes.…”

Section: Hasil Penelitian Dan Pembahasan a Hasilunclassified

Edukasi Pemberian Jus Kulit Manggis Terhadap Kestabilan Kadar Glukosa Darah Pasien Diabetes Mellitus Tipe II

Batubara¹,

Sinaga²,

Sianturi³

2023

Creat J. Cumn Enga

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ABSTRAK Pasien Diabetes Tipe II ditandai dengan adanya peningkatan Kadar Glukosa dalam Darah. Xanton merupakan senyawa bioaktif pada kulit buah manggis yang diperkirakan mempunyai efek antidiabetes. Studi fitokimia telah menunjukkan bahwa mereka mengandung berbagai metabolit sekunder, seperti oksigen dan terprenilasi xanthones. Berdasarkan studi pendahuluan yang telah dilakukan di Wilayah Kerja Puskesmas Sibolangit dengan melakukan wawancara pada 10 orang penderita Diabetes Mellitus Tipe II, sebagian besar mengatakan jika kadar glukosa darah meningkat hanya meminum obat yang telah diberikan pihak Rumah Sakit dan tidak pernah mengetahui manfaat dari jus kulit manggis dapat mengatasi kestabilan kadar glukosa darah. Tujuan dari edukasi yang dilakukan adalah meningkatkan pengetahuan penderita Diabetes Mellitus Tipe II dalam pembuatan jus kulit manggis. Metode dalam pengabdian ini adalah dengan melakukan pendampingan cara pembuatan jus kulit manggis secara langsung oleh pengabdi. Sasaran dalam pengabdian ini adalah penderita Diabetes Mellitus Tipe II di Wilayah Kerja Puskesms Sibolangit. Setelah dilakukan penyuluhan dan pendampingan akan dievaluasi hasil edukasi yang telah diberikan dengan menggunakan kuesioner untuk mengevaluasi pengetahuan penderita Diabetes Mellitus Tipe II tentang manfaat jus kulit manggis untuk kestabilan Kadar Glukosa Darah setelah 1 minggu mengkonsumsi jus kulit manggis dan dievaluasi penurunan kadar glukosa darahnya. Hasil pengukuran pengetahuan penderita Diabetes Mellitus Tipe II sebelum dan sesudah edukasi meningkat sebesar 7,9. Kesimpulan evaluasi hasil kadar glukosa darah pasien Diabetes Tipe II mengalami penurunan yaitu rata-rata 2.00 mg/dl. Kata Kunci: Edukasi Pemberian Jus Kulit Manggis, Pengetahuan, Kadar Glukosa Darah ABSTRACT Type II Diabetes patients are characterized by an increase in blood glucose levels. Xanthones are bioactive compounds in mangosteen rind which are thought to have antidiabetic effects. Phytochemical studies have shown that they contain various secondary metabolites, such as oxygen and prenylated xanthones. Based on a preliminary study that was conducted in the Sibolangit Health Center Work Area by conducting interviews with 10 people with Type II Diabetes Mellitus, most said that if blood glucose levels increased, they only took the medicine that had been given by the hospital and never knew the benefits of mangosteen peel juice. stabilize blood glucose levels. The purpose of the education conducted is to increase the knowledge of Type II Diabetes Mellitus sufferers in making mangosteen rind juice. The method in this service is to provide assistance on how to make mangosteen peel juice directly by the servant. The targets in this service are people with Diabetes Mellitus Type II in the Working Area of the Sibolangit Health Center. After counseling and mentoring will be evaluated the results of the education that has been given using a questionnaire to evaluate the knowledge of Type II Diabetes Mellitus sufferers about the benefits of mangosteen peel juice for stability of blood glucose levels after 1 week of consuming mangosteen peel juice and evaluated for a decrease in blood glucose levels. The results of measuring the knowledge of people with Diabetes Mellitus Type II before and after education have increased of 7,9. The conclusion of the evaluation of the results of blood glucose levels in Type II Diabetes patients has decreased, namely an average of 2.00 mg/dl. Keywords: Education on Giving Mangosteen Peel Juice, Knowledge, Blood Glucose Levels

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Penurunan Kadar Gula Darah Akibat Pemberian Ekstrak Manggis (<i>Garcinia mangostana</i>) dan Tomat (<i>Lycopersicum esculentum Mill</i>) pada Tikus Diabetes

Cited by 4 publications

References 1 publication

Effect of tomato and red guava juice on blood glucose level in overweight woman

Effect of tomato and red guava juice on blood glucose level in overweight woman

Effect of palm sap (Arenga pinnata) on blood glucose levels of mice (Mus musculus) alloxan-induced diabetic

Edukasi Pemberian Jus Kulit Manggis Terhadap Kestabilan Kadar Glukosa Darah Pasien Diabetes Mellitus Tipe II

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