PERBANDINGAN UJI AKTIVITAS ANTIBAKTERI MINYAK ATSIRI DAUN, TANGKAI BUNGA DAN BUNGA CENGKEH BALI (Syzygium aromaticum L.) TERHADAP BAKTERI Propionibacterium acne DENGAN METODE DIFUSI DISK

Lova, I. P. S. T.; Wijaya, Wiwin; Paramita, Ni Luh Putu Vidya; Putra, Aan Andri

doi:10.24843/jchem.2018.v12.i01.p06

Cited by 6 publications

(6 citation statements)

References 1 publication

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“…Research conducted by Lova et al (2018) on clove flower essential oil to bacteria was able to produce the greatest antibacterial activity, namely 25.85 mm -26.75 mm while flower stalk essential oil produced activity with an inhibition zone of 20.60 mm -21, 20 mm and clove essential oil produced an inhibition zone of 18.04 mm -18.58 mm. This proves that the essential oil from the clove flower has the best activity against P.acnes s compared to the essential oil from the flower stalk and clove leaf.…”

Section: Resultsmentioning

confidence: 98%

Effect of Ethanol Extract from Clove Flower (Syzygium aromaticum) on the Growth of Trichophyton rubrum in vitro

2021

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Indonesia is one of the countries with a tropical climate that has high temperature and humidity, a good atmosphere for fungal growth so that fungi can be found somewhere. Fungus Trichophyton rubrum is a fungal disease that attacks the nails, skin, hair. One of the preventions of this disease is by giving traditional medicines, namely clove flowers (Syzygium aromaticum) which contain chemical compounds saponins, tannins, flavonoids. Serves as an antioxidant that can prevent dermatosis. The purpose of this study was to determine the inhibition power of clove flowers (Syzygium aromaticum) on the growth of Trichophyton rubrum fungi. This research was carried out an experimental method with the Kirby Bauer method. Concentration dilution of clove ethanol extract (Syzygium aromaticum) from concentration 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, 100%. The results of this study showed that the clove ethanol extract (Syzygium aromaticum) inhibit the growth of Trychophyton rubrum fungus from the concentration of 10% inhibition zone 14 mm, 20% inhibition zone 26 mm, 30% inhibition zone 36 mm, 40% inhibition zone 41 mm, 50% 45 mm inhibition zone, 60% 46 mm inhibition zone, 70% 48 mm inhibition zone, 80% 49 mm inhibition zone, 90% 51.0 mm inhibition zone, 100% inhibition zone of 56 mm.

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Section: Resultsmentioning

confidence: 98%

Effect of Ethanol Extract from Clove Flower (Syzygium aromaticum) on the Growth of Trichophyton rubrum in vitro

2021

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“…Hal ini dapat diperparah oleh infeksi bakteri penyebab patogenesis jerawat, bakteri tersebut akan menyebabkan peradangan pada kulit wajah. Diantara berbagai jenis bakteri yang menyebabkan patogenesis jerawat, Propionibacterium acnes merupakan bakteri yang paling dominan (Lova dkk., 2018).…”

Section: Aunclassified

Formulasi Sediaan Masker Clay Peel Off Ekstrak Daun Sirsak (Annona muricata L.) sebagai Antijerawat

Waliasih

Aryani

Dewi

2022

BCSP

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Abstract. Acne is a health problem that is often found on the skin and bothers both physically and psychologically. Based on previous research, soursop leaves have activity against the bacteria Propionibacterium acnes which is the bacteria that causes acne. The purpose of this study was to make a clay peel off mask formulation containing ethanolic extract of soursop leaves as an anti-acne. In this study, soursop leaf extract was made with 95% ethanol solvent using the maceration method. Extract activity test against P. acnes was carried out using the diffusion method so that the well method produced a MIC value at a concentration of 0.06% with an inhibitory diameter of 8.81 mm. The manufacture of clay peel off masks from soursop leaf ethanol extract was made based on the gelation reaction between sodium alginate and calcium sulfate. Clay peel off mask with a concentration of 15% ethanolic extract of soursop leaves is the most optimum formulation based on pharmaceutical evaluation and is known to have antibacterial activity against P. acnes. Abstrak. Jerawat merupakan masalah kesehatan yang sering ditemukan pada kulit dan mengganggu baik secara fisik maupun psikis. Berdasarkan penelitian sebelumnya, daun sirsak memiliki aktivitas terhadap bakteri Propionibacterium acnes yang merupakan bakteri penyebab jerawat. Tujuan dari penelitian ini untuk membuat formulasi sediaan masker clay peel off mengandung ekstrak etanol daun sirsak sebagai antijerawat. Pada penelitian ini dilakukan pembuatan ekstrak daun sirsak dengan pelarut etanol 95% menggunakan metode maserasi. Uji aktivitas ekstrak terhadap P. acnes dilakukan dengan metode difusi agar cara sumuran menghasilkan nilai KHM pada konsentrasi 0,06% dengan diameter hambat sebesar 8,81 mm. Pembuatan masker clay peel off ekstrak etanol daun sirsak dibuat berdasarkan reaksi gelasi antara natrium alginat dan kalsium sulfat. Masker clay peel off dengan konsentrasi 15% ekstrak etanol daun sirsak merupakan formulasi yang paling optimum berdasarkan evaluasi farmasetik dan diketahui memiliki aktivitas antibakteri terhadap P. acnes.

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“…Penelitian yang dilakukan oleh Mohammed (2015) mengenai aktivitas antibakteri kurkumin terhadap bakteri Gram positif Streptococcus mutans dan Streptococcus pyogenes, masing masing dengan zona hambat sebesar 9,7mm dan 10,2mm (Mohammed, 2015). Sedangkan uji mengenai efektivitas minyak atsiri pada daun, tangkai bunga, dan daun cengkeh Bali terhadap Propionibacterium acnes dilakukan oleh Lova (2017) dan diperoleh hasil diameter zona hambat sebesar ≥18,04mm (Lova, 2017). Hasil penelitian Mohammed (2015) dan Lova (2017) tersebut mendukung hasil penelitian ini yang menunjukkan terdapat efek antibakteri Propionibacterium acnes sebagai bakteri Gram positif setelah pemberian ekstrak rimpang kunyit secara in vitro.…”

Section: Pembahasanunclassified

Uji Efektivitas Antibakteri Ekstrak Rimpang Kunyit (Curcuma domestica Val.) terhadap Pertumbuhan Propionibacterium acnes In Vitro

Cahyani

Anggraini

Soleha

et al. 2020

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One of the treatments for acne vulgaris therapy is antibiotics, it can be applied topically and systemically. However, long-term and inappropriate use of antibiotics can increase the incidence of antibiotic drug resistance. Some medicinal plants are known to have antimicrobial properties, one of them is turmeric rhizome. Turmeric rhizome is known to contain essential oils and curcumin so that it can be useful as an antibacterial, antiviral, anti protozoa, anti-inflammatory, antioxidant, and antineoplasm. This study aims to determine the effectiveness of the antibacterial turmeric extract against the growth ofÂ Propionibacterium acnes. The type of this research is an experimental laboratory with disc diffusion method on Mueller Hinton Agar media. Turmeric extract was obtained from the Laboratory of Organic Chemistry at the University of Lampung with maceration techniques using 96% ethanol. Turmeric rhizome extract is divided into several concentrations namely 15%, 30%, 50%, 75%, and 100%. As negative control is aquades and positive control is clindamycin. Data was obtained based on the result of measurement Diameter of inhibition zone made through paper discs and measured by calipers. The data were analyzed by using One Way ANOVA. The result of this study indicated that the diameter of the inhibits zone at a concentration of 15%, 30%, 50%, 75%, and 100%. Sequentially is 11,35mm, 15,65mm, 17,575mm, 18,85mm, and 20,8mm. in the negative control is 0 mm and positive control is 28,1 mm (score p-value=0,000). There is antibacterial effectiveness of turmeric extract against the growth ofÂ Propionibacterium acnesÂ in vitro, but it is no superior compared with clindamycin phosphate.

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PERBANDINGAN UJI AKTIVITAS ANTIBAKTERI MINYAK ATSIRI DAUN, TANGKAI BUNGA DAN BUNGA CENGKEH BALI (Syzygium aromaticum L.) TERHADAP BAKTERI Propionibacterium acne DENGAN METODE DIFUSI DISK

Cited by 6 publications

References 1 publication

Effect of Ethanol Extract from Clove Flower (Syzygium aromaticum) on the Growth of Trichophyton rubrum in vitro

Effect of Ethanol Extract from Clove Flower (Syzygium aromaticum) on the Growth of Trichophyton rubrum in vitro

Formulasi Sediaan Masker Clay Peel Off Ekstrak Daun Sirsak (Annona muricata L.) sebagai Antijerawat

Uji Efektivitas Antibakteri Ekstrak Rimpang Kunyit (Curcuma domestica Val.) terhadap Pertumbuhan Propionibacterium acnes In Vitro

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