“…Percolation theory is, in fact, the most suitable tool to predict and simulate the geometrical phase transitions in a complex multi‐particulate system and allows finding the regions where the system undergoes transitional changes in its properties. In terms of solid dosage form design, such regions usually are linked to extreme values of drug dissolution rate, tablet disintegration time, tablet water uptake, etc 12, 14, 19–21. According to percolation theory, a transitional change happens at a critical concentration of components in a system when one component forms an infinite cluster propagating through the entire system (i.e., percolates).…”