Ventricular septal rupture (VSR) is a rare but critical complication that usually occurs within 1 week after acute myocardial infarction (AMI) [1]. Patients without surgical repair of VSR show a high mortality rate of 76% within 1 month, and emergency surgical repair is necessary. However, the in-hospital mortality rate is still high at 47%, and depends on the patient's preoperative condition [2,3]. Here, we describe the successful transcatheter closure of a recurrent post-infarction VSR using an Amplatzer duct occluder (ADO) in a patient who had undergone emergency surgical repair. Case report A 78-year-old woman was referred to our hospital with cardiogenic shock 2 days after the first episode of chest pain. Upon hospital admission, her blood pressure was 78/52 mmHg and her pulse rate was 104 beats/min. Physical examination revealed internal jugular venous dilatation and a grade 3 pan-systolic murmur at the apex. Her 12-lead electrocardiogram showed ST elevation in leads V2-V5. Echocardiography in the emergency room revealed akinesis in the mid anterior septum and apex, and VSR in the apical interventricular septum with left-to-right shunt