Percutaneous endovascular biopsy in the diagnosis of venous sinus lesions: technical note

Abstract

Intracranial hypertension (IH) may be misdiagnosed owing to the lack of typical imaging features and pathological confirmation of the sinus lesions. The authors report the use of percutaneous endovascular biopsy (PEB) for the diagnosis of IH in patients with venous sinus lesions. A total of 9 patients (age 46 ± 9 years) underwent PEB between June 2016 and August 2017. All patients underwent lumbar puncture and contrast-enhanced MRI before the procedure. PEB was technically successful in 6 patients. No intra- or postprocedural complications occurred. The confirmed lesions were meningioma in 2 patients and fibrous thrombus in 4 patients. All patients received individualized treatment. PEB of venous sinus lesions is a safe and efficient method to establish an early diagnosis and appropriate treatment in patients with IH.

Functionalized Spiral‐Rolling Millirobot for Upstream Swimming in Blood Vessel

“…[21,22] However, realizing the controllable locomotion of these robots inside blood vessels is still challenging, let along conducting in vivo medical tasks, such as drug delivery and biopsy. [23][24][25][26][27] Here, we present an untethered millirobot with a streamlined shape (Figure 1; Video S1, Supporting Information), whose biocompatibility and safety were confirmed by the cell viability test on L929 cells and the histological results of rabbit abdominal arteries. Remotely driven by the magnetic field (magnetic flux density ≈ 12 mT, magnetic field gradient ≈ 45 Gs cm −1 ), our robot can Figure 1.…”

“…[ 21,22 ] However, realizing the controllable locomotion of these robots inside blood vessels is still challenging, let along conducting in vivo medical tasks, such as drug delivery and biopsy. [ 23–27 ]…”

Venous Manometry as an Adjunct for Diagnosis and Multimodal Management of Intracranial Hypertension due to Meningioma Compressing Sigmoid Sinus

“…Intracranial hypertension caused indirectly by a mass compressing part of the intracranial dural sinuses, resulting in obstruction of venous drainage, has been described [2-3]. Intracranial hypertension due to a mass compressing the dural sinuses should be distinguished from idiopathic intracranial hypertension which requires an increase in the intracranial pressure of more than 20 cm H2O, in the setting of normal ventricular size, absence of an intracranial mass and absence of neurological deficits [8]. The mechanism by which compression of the dural sinuses result in increased intracranial pressure is explained by the modified Kellie-Monroe doctrine, which states that the sum of intracranial volumes is constant, and that an increase in any component must be offset by an equal decrease in another component [9].…”