Perfil Fitoquímico, Atividades Citotóxica E Genotóxica Do Extrato Aquoso De Rhizophora Mangle L / Phytochemical Screening, Cytotoxic and Genotoxic Activity of the Aqueous Extract of Rhizophora Mangle L

Lima, Gustavo da Costa; Costa, Marcos Aurélio Santos da; Júnior, João B. da S.; Silva, Raquel Barbosa da; Souza, Ivone Antônia de; Oliveira, Antônio Fernando Morais de; Medeiros, Juliana Pinto de

doi:10.34117/bjdv7n3-377

Cited by 2 publications

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“…[9] The species is traditionally used to treat gastric disorders, with antifungal and antiulcerogenic properties, [28] as well as against hemorrhages, episodes of diarrhea, diabetes, cholesterol, high blood pressure, and toothaches. [29,30] This plant, typical of mangrove ecosystems, has varied uses in folk medicine, mainly in water infusions. Scientific studies on the potential of R. mangle as a medicinal therapeutic agent are also present.…”

Section: Introductionmentioning

confidence: 99%

Dereplication Tools for Rhizophora mangle Extracts from Different Mangrove Areas and their Potential Against Staphylococcus aureus

da Silva Pontes,

Monteiro Leal,

Pereira Lucas

et al. 2024

Chemistry & Biodiversity

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Rhizophora extracts have several potential biological activities, and their metabolites can be used in the pharmaceutical industry. Extracts of Rhizophora species obtained from mangroves have shown prospective activity against Staphylococcus aureus. This study aimed to investigate the chemical profile of Rhizophora mangle leaves from fringe, basin, and transition mangrove zones and their bactericidal/bacteriostatic potential against S. aureus. R. mangle leaves were collected monthly in 2018 from litterfall in three different zones of the mangrove of Guaratiba State Reserve: fringe, basin, and transition. Extracts were prepared from the material collected in October and December for LC‐HRMS/MS analysis, and dereplication was performed using a molecular library search and the classical molecular networking GNPS platform. The minimum inhibitory concentrations (MICs) of the aqueous extract of R. mangle against S. aureus were determined. No S. aureus growth was observed compared to the control for extracts collected from September to December. Different compounds were annotated in each region, yet a marked presence of phenolic compounds was noted, among them glycosylated flavonoid derivatives of quercetin and kaempferol. The results suggest bactericidal/bacteriostatic activity for extracts of R. mangle leaves collected in 2018 from three mangrove forest zones.

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Section: Introductionmentioning

confidence: 99%

Dereplication Tools for Rhizophora mangle Extracts from Different Mangrove Areas and their Potential Against Staphylococcus aureus

da Silva Pontes,

Monteiro Leal,

Pereira Lucas

et al. 2024

Chemistry & Biodiversity

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“…Antioxidants play a fundamental role in precluding the oxidation of molecules vital for life by preventing them from chemically interacting with reactive oxygen species (ROS) . Therefore, the plant’s antioxidant properties are an option for problem-solving strategies in laboratory experiments since there are several chemical concepts related to the characterization of chemical compounds and determination of the antioxidant capacity of the plant. − …”

Section: Introductionmentioning

confidence: 99%

Antioxidant Capacity ofRhizophora mangleBark Extracts: A Contextualized Approach in the Teaching of Analytical Chemistry

Damm,

Schaffel,

Santos

et al. 2023

J. Chem. Educ.

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Antioxidants are molecules that act against free radicals, and this effect can bring many benefits to health and society. Antioxidants can be found in various matrices of nature, such as fruits and plants. Some studies have shown that Rhizophora mangle, a typical mangrove plant, is rich in antioxidants. People report its use for medicinal purposes, such as treating diabetes and high blood pressure. In Espi ́rito Santo, Brazil, the bark extract of the plant is used as a waterproofing agent in the making of the capixaba clay pan, a cultural symbol of the state. Thus, this context was used as a reference for the application of chemical knowledge addressed in the teaching of Instrumental Analytical Chemistry. The participants were undergraduate chemistry students at the Federal University of Espi ́rito Santo (Ufes). Two experiments were designed to be performed by groups of four to five students during 2−4 h laboratory classes. The students employed analytical techniques for spectrophotometric (FRAP, ferric reducing antioxidant power) and electrochemistry (CRAC, ceric reducing antioxidant capacity) determination of the total antioxidant capacity of R. mangle bark extracts. The experimental results indicated that the extracts of the plant have significant antioxidant capacity compared to trolox. By performing different extraction procedures and analytical techniques, students were able to compare, analyze, and evaluate strategies aimed at determining antioxidant capacity. The antioxidant capacity assays can be expanded to analyze other matrices of interest to professors and students.

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Perfil Fitoquímico, Atividades Citotóxica E Genotóxica Do Extrato Aquoso De Rhizophora Mangle L / Phytochemical Screening, Cytotoxic and Genotoxic Activity of the Aqueous Extract of Rhizophora Mangle L

Cited by 2 publications

References 0 publications

Dereplication Tools for Rhizophora mangle Extracts from Different Mangrove Areas and their Potential Against Staphylococcus aureus

Dereplication Tools for Rhizophora mangle Extracts from Different Mangrove Areas and their Potential Against Staphylococcus aureus

Antioxidant Capacity ofRhizophora mangleBark Extracts: A Contextualized Approach in the Teaching of Analytical Chemistry

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