Performance of a new rapid diagnostic test the lactate/glucose ratio of synovial fluid for the diagnosis of septic arthritis

Berthoud, Olivia; Coiffier, Guillaume; Albert, Jean-David; Gougeon-Jolivet, Anne; Goussault, Claire; Bendavid, Claude; Guggenbuhl, Pascal

doi:10.1016/j.jbspin.2020.03.009

Cited by 16 publications

(11 citation statements)

References 34 publications

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“…In some cases, the possibility of bacterial contamination of the collected material can be considered, especially when the clinical signs are not compatible, and the isolated bacterium is not likely. In these cases, it is recommended to monitor the patient through imaging tests and clinical evaluations without antibiotics 40 .…”

Section: Discussionmentioning

confidence: 99%

Bilateral septic arthritis of the shoulder: case report and literature review

Maia¹,

Silva²,

Santos³

et al. 2021

Arch Health Invest

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Bilateral shoulder septic arthritis is a rare condition in immunocompetent patients without known risk factors, therefore, it can be easily misdiagnosed. Septic arthritis is an emergency due to its potential to cause rapid destruction of cartilage and bone as well as the risk for systemic spread. Aggressive early treatment is crucial for easing pain, preventing joint collapse, and permanent loss of shoulder function. We presented a case report of a 68 years-old man, suffering from multiple comorbidities and bilateral shoulder septic arthritis. The patient underwent arthroscopic surgery in the left shoulder. Antibiotic therapy was carried out after the surgical procedure using clindamycin. The patient had a satisfactory outcome, characterized by regression of the inflammatory symptoms in both shoulders. There was an improvement in pain and fevers settled. In this case report, we have also discussed treatment options as well as possible outcomes.

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Section: Discussionmentioning

confidence: 99%

Bilateral septic arthritis of the shoulder: case report and literature review

Maia¹,

Silva²,

Santos³

et al. 2021

Arch Health Invest

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“…The rapid diagnostic test strip has many advantages, such as simple operation, low cost, and fast detection speed [ 93 ]. This detection method has been widely used in many point-of-care testings (POCT) applications [ 94 , 95 ].…”

Section: Serology-based Detection Methodsmentioning

confidence: 99%

Recent advances in detection technologies for COVID-19

Han

Cong

Shen

et al. 2021

Talanta

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Corona Virus Disease 2019 (COVID-19) is a highly infectious respiratory illness that was caused by the SARS-CoV-2. It spread around the world in just a few months and became a worldwide pandemic. Quick and accurate diagnosis of infected patients is very important for controlling transmission. In addition to the commonly used Real-time reverse-transcription polymerase chain reaction (RT-PCR) detection techniques, other diagnostic techniques are also emerging endlessly. This article reviews the current diagnostic methods for COVID-19 and discusses their advantages and disadvantages. It provides an important reference for the diagnosis of COVID-19.

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“…In the literature of the recent years, the results of mono- and complex researches reflecting clinical-morphological, immunological, and chemical SF compositions have been presented. For example, there appeared the works devoted to the study of immune cells [ 6 ], glucose level, activity of hyaluronidase, alkaline phosphatase, and lactate dehydrogenase in SF [ 7 ], proteome profile [ 8 - 10 ], and carbohydrate composition of synovia [ 11 ] in different articular pathologies. These data underlines to some extent a marked clinical-pathogenetic significance of almost each of the aforementioned indices.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Pathogenetic Significance of Amylase Level and Microtomographic Index of Synovial Fluid in Various Joint Lesions

Schendrigin¹,

Timchenko²,

Rzhepakovsky³

et al. 2022

Sovrem Tehnol Med

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The aim of the investigation was to study the level of amylolytic activity and microtomographic index of synovial fluid density as well as to substantiate their clinical and pathogenetic significance by identifying correlations with the known informative indicators reflecting characteristic features of the pathological process in various joint diseases.Materials and Methods. Samples of synovial fluid from 95 patients with various joint pathologies at the stage of the disease progression characterized by copious effusion into articular cavities have been examined. Synovial fluid samples obtained by knee arthrocentesis served as a material for the investigation. Conventional methods were used to determine the concentration of uric acid, inorganic phosphorus, total protein, and amylolytic activity level in the selected samples while X-ray density was identified by computed microtomography.Results. All samples of pathological joint fluid have shown a high level of amylolytic activity as compared to the synovial fluid from healthy joints. The relationship between the level of amylolytic activity in synovia and specific joint pathology has been identified. It has also been found that uric acid values, inorganic phosphorus concentrations, and total protein in various types of joint damage may influence X-ray density of the synovial fluid. Correlations between the studied indices have been established. Conclusion.New data on the level of synovia amylolytic activity has been obtained in one non-inflammatory and six different inflammatory diseases. Pathogenically determined correlation between the microtomographic index of synovial fluid density and concentrations of uric acid, inorganic phosphorus, total protein has been confirmed. Specific indicators of X-ray density of synovia in various joint pathologies as well as unidirectional and multidirectional data in comparison with the norm allow us to consider X-ray microtomography as a method that reveals additional details during investigation of synovial fluid density and brings new surrogate markers for the study of pathogenetic mechanisms of the development, differentiation, and treatment of various joint pathologies.

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Performance of a new rapid diagnostic test the lactate/glucose ratio of synovial fluid for the diagnosis of septic arthritis

Abstract: Performance of a new rapid diagnostic test the lactate/glucose ratio of synovial fluid for the diagnosis of septic arthritis.

Cited by 16 publications

References 34 publications

Bilateral septic arthritis of the shoulder: case report and literature review

Bilateral septic arthritis of the shoulder: case report and literature review

Recent advances in detection technologies for COVID-19

Clinical and Pathogenetic Significance of Amylase Level and Microtomographic Index of Synovial Fluid in Various Joint Lesions

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