Performance of femtosecond laser-assisted cataract surgery in Chinese patients with cataract: a prospective, multicenter, registry study

Abstract

BackgroundThis study aimed to investigate the completion rate, visual performance, and adverse outcomes of femtosecond laser-assisted cataract surgery (FLACS) in Chinese patients.MethodsThis is a prospective, single-arm, multicenter registry study of 19 cataract surgery clinics in China. Chinese patients with cataract who underwent FLACS using the Alcon LenSx® laser system in single eye (n = 1140) or both eyes (n = 201) were enrolled and data were collected between March 2015 and August 2016. Clinical characteristics were recorded before surgery, and on postoperative days 1, 7, and 30. For surgery on both eyes, the second eye was included in the analysis only if it was operated within 30 days after the first eye surgery. The primary outcome was the completion rate of circular anterior capsulotomy. Secondary outcomes for lens fragmentation, corneal incision, and intraocular lens (IOL) implantation included best corrected distance visual acuity (BCDVA) and completion rates. Adverse events (AEs) were recorded.ResultsThe completion rates of circular anterior capsulotomy, lens fragmentation, corneal incision, and IOL implantation were 98.6% (95% CI: 97.8–99.1%), 99.5% (95% CI: 99.1–99.8%), 97.6% (95% CI: 96.7–98.3%), and 100% (95% CI: 99.8–100%), respectively. BCDVA preoperatively and at postoperative day 30 were 1.134 ± 0.831 logMAR and 0.158 ± 0.291 logMAR, respectively. The proportion of eyes with BCDVA of 20/20 or better was 1.6% at baseline and 41.3% at postoperative day 30. AE incidence was 0.32%, with posterior capsule rupture present in 0.19% of eyes.ConclusionFLACS using the LenSx® laser system can achieve satisfactory results in a real-world setting.Electronic supplementary materialThe online version of this article (10.1186/s12886-019-1079-0) contains supplementary material, which is available to authorized users.

Protective effect of bromfenac sodium on femtosecond laser‑assisted cataract surgery via modulating cyclooxygenase‑2 expression

“…Tissue injuries such as endothelial cell loss and macular edema are frequently induced during surgery (22). Previous studies have reported that the use of FLACS has fewer complications and is more reliable compared with CPCS (23). The present results suggested that there was no difference in CDVA, as well as aqueous flare, between CPCS groups and FLACS groups.…”

Distribution of ocular biometric parameters and optimal model of anterior chamber depth regression in 28,709 adult cataract patients in China using swept‐source optical biometry

“…The result, which indicated that there was a higher ratio of cataract patients under 70 years of age currently than there was 10 years ago, was statistically significant (χ 2 = 199.008, P < 0.001). Over the last 10 years, the development of phacoemulsification and femtosecond laser-assisted cataract surgery [ 13 , 14 ] and the popularity of functional intraocular lenses [ 15 , 16 ] have advanced cataract surgery in China, leading to better visual outcomes. Urban Chinese cataract patients in the present study tended to choose surgical treatment earlier than cataract patients did 10 years ago, a decision which could improve their quality of life.…”

Intra and post-operative complications observed with femtosecond laser-assisted cataract surgery versus conventional phacoemulsification surgery: a systematic review and meta-analysis

“…However, we should not forget the fact that complications such as vitreous loss might be reduced with FLACS [17] and therefore, its complications should not be overestimated but instead, we should also pay attention to its beneficial features. Also, FLACS using the LenSx laser system might achieve better results in a real world setting [18].…”