Peri-implant bone reactions around immediately loaded conical implants with different prosthetic suprastructures: histological and histomorphometrical study on minipigs

Abstract

The aim of this study was to evaluate peri-implant bone reactions around immediately loaded conical implants with metal and acrylic resin prosthetic restorations. Five splinted conical implants were inserted in each hemimandible of six minipigs at the alveolar crest level. Ten implants were inserted in each minipig. All the implants were immediately loaded. The implants were divided into a group with an acrylic resin prosthetic restoration and into another group with a metal prosthetic restoration. No postoperative complications or deaths of the minipigs occurred. All minipigs were killed after 3 months. No implant was lost. A total of 60 implants were retrieved and processed to obtain thin ground sections. Histology and histomorphometry showed the presence of compact, mature bone around all the implants. Bone was in close contact with the implant surface starting from the first or second implant threads. A high quantity of mineralized bone was present around immediately loaded conical, root form implants. No differences in the peri-implant bone response were found in the groups with different prosthetic reconstructions.

The effect of loading in regenerated bone in dehiscence defects following a combined approach of bone grafting and GBR

“…These results provide support to the notion that regenerated bone functions in the same manner under functional loading as native/pristine bone does and positive changes in term of BIC can be expected following loading (Assenza et al. Berglundh et al. ).…”

Impact of vertical loading on the implant‐bone interface

“…The bone‐implant contact with around 80% was comparable to results from the literature (Assenza et al. ). The cracks only were found in the SEM specimens with native bone embedded.…”

Twist removal of healed vs. nonhealed implants—a mechanical and histological study in mini pigs

“…Previous in vivo assessments of bone healing around implants presented histological observations such as bone-implant contact studies under monitored torque values [19, 22, 37]. This study adds an extended methodology of previous investigations, because it provides beyond histological analysis and immunohistochemical analysis to assess peri-implant bone behavior in a real clinical condition.…”

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