Perineuronal satellitosis in the human hippocampal formation

Vijayan, Vijaya K.; Zhou, Shanshan; Russell, Michael J.; Geddes, Jim; Ellis, William G.; Cotman, Carl W.

doi:10.1002/hipo.450030215

Cited by 32 publications

(24 citation statements)

References 33 publications

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“…Together, our findings indicate that avian PGCs are both region- and taxon-specific, suggesting that their presence in healthy passerines and humans (as shown by Brownson, 1956; Vijayan et al, 1993; van Landeghem, Weiss & von Deimling, 2007; Vostrikov, Uranova & Orlovskaya, 2007) may be the result of convergent evolution.…”

Section: Resultsmentioning

confidence: 59%

“…6 in Fortune & Margoliash, 1992). However, PGCs do resemble the perineuronal satellitosis described previously in the human hippocampus, i.e., “... clustering of glial nuclei was observed along one border or around the periphery of several neuronal perikarya ...” (see Vijayan et al, 1993). …”

Section: Resultsmentioning

confidence: 65%

“…Satellite glia were first described by Ramón y Cajal (1910) and Ramón y Cajal (1899) in healthy peripheral nervous tissue and in the 1930s the term perineuronal satellitosis (PS) was coined to describe neurons closely surrounded by multiple glia (see Vijayan et al, 1993). Today, most neuropathology textbooks teach us to recognise PS in the process of diagnosis of common pathologies that affect the nervous tissue (e.g., grade II astrocytoma, type I neurofibromatosis and anaplastic oligodendroglioma) (Haberland, 2007; Oemichen, Auer & König, 2006; Perry & Brat, 2010; Tonn, Westphal & Rutka, 2010).…”

Section: Introductionmentioning

confidence: 99%

“…Satellite glia are, however, associated both with normal and pathological nervous tissue depending on the function and the type of perineuronal glia involved (Ludwin, 1984; Yokota et al, 2008; Faber-Zuschratter et al, 2009; Takasaki et al, 2010; Szuchet et al, 2011). Perineuronal (and polar) satellite glia have been described in healthy tissue in different regions of the human brain such as the cerebral cortex, hippocampus, basal ganglia and thalamus (Brownson, 1956; Vijayan et al, 1993; Vostrikov, Uranova & Orlovskaya, 2007). Satellite glia present in these brain areas mostly correspond to oligodendrocytes (Brownson, 1956; Vijayan et al, 1993; van Landeghem, Weiss & von Deimling, 2007; Vostrikov, Uranova & Orlovskaya, 2007; Kim & Webster, 2010; Kim & Webster, 2011; Takasaki et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

“…Perineuronal (and polar) satellite glia have been described in healthy tissue in different regions of the human brain such as the cerebral cortex, hippocampus, basal ganglia and thalamus (Brownson, 1956; Vijayan et al, 1993; Vostrikov, Uranova & Orlovskaya, 2007). Satellite glia present in these brain areas mostly correspond to oligodendrocytes (Brownson, 1956; Vijayan et al, 1993; van Landeghem, Weiss & von Deimling, 2007; Vostrikov, Uranova & Orlovskaya, 2007; Kim & Webster, 2010; Kim & Webster, 2011; Takasaki et al, 2010). In addition, a reduction in the number of perineuronal oligodendrocytes (pN-OLG) in the human prefrontal cortex has recently been linked to schizophrenia and other psychiatric disorders (Vostrikov, Uranova & Orlovskaya, 2007; Kim & Webster, 2010; Kim & Webster, 2011).…”

Section: Introductionmentioning

confidence: 99%

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Perineuronal satellite neuroglia in the telencephalon of New Caledonian crows and other Passeriformes: evidence of satellite glial cells in the central nervous system of healthy birds?

Medina

Hunt

Gray

et al. 2013

PeerJ

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Glia have been implicated in a variety of functions in the central nervous system, including the control of the neuronal extracellular space, synaptic plasticity and transmission, development and adult neurogenesis. Perineuronal glia forming groups around neurons are associated with both normal and pathological nervous tissue. Recent studies have linked reduction in the number of perineuronal oligodendrocytes in the prefrontal cortex with human schizophrenia and other psychiatric disorders. Therefore, perineuronal glia may play a decisive role in homeostasis and normal activity of the human nervous system.Here we report on the discovery of novel cell clusters in the telencephala of five healthy Passeriforme, one Psittaciform and one Charadriiforme bird species, which we refer to as Perineuronal Glial Clusters (PGCs). The aim of this study is to describe the structure and distribution of the PGCs in a number of avian species.PGCs were identified with the use of standard histological procedures. Heterochromatin masses visible inside the nuclei of these satellite glia suggest that they may correspond to oligodendrocytes. PGCs were found in the brains of nine New Caledonian crows, two Japanese jungle crows, two Australian magpies, two Indian mynah, three zebra finches (all Passeriformes), one Southern lapwing (Charadriiformes) and one monk parakeet (Psittaciformes). Microscopic survey of the brain tissue suggests that the largest PGCs are located in the hyperpallium densocellulare and mesopallium. No clusters were found in brain sections from one Gruiform (purple swamphen), one Strigiform (barn owl), one Trochiliform (green-backed firecrown), one Falconiform (chimango caracara), one Columbiform (pigeon) and one Galliform (chick).Our observations suggest that PGCs in Aves are brain region- and taxon-specific and that the presence of perineuronal glia in healthy human brains and the similar PGCs in avian gray matter is the result of convergent evolution. The discovery of PGCs in the zebra finch is of great importance because this species has the potential to become a robust animal model in which to study the function of neuron-glia interactions in healthy and diseased adult brains.

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Section: Resultsmentioning

confidence: 59%

Section: Resultsmentioning

confidence: 65%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Perineuronal satellite neuroglia in the telencephalon of New Caledonian crows and other Passeriformes: evidence of satellite glial cells in the central nervous system of healthy birds?

Medina

Hunt

Gray

et al. 2013

PeerJ

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Neuron numbers in the presubiculum, parasubiculum, and entorhinal area of the rat

1997

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Estimates of neuron numbers have been useful in studies of neurodegenerative disorders, and in their animal models, and in the computational modeling of hippocampal function. Although the retrohippocampal region (presubiculum, parasubiculum, and entorhinal area) is an integral part of the hippocampal circuitry and is affected selectively in a number of disorders, estimates of neuron numbers in the rat retrohippocampal region have yet to be published. Such data are necessary ingredients for computational models of the function of this region and will also facilitate a comparison of this region in rats and primates, which will help to determine how well we may expect rat models to predict function and dysfunction in primate brains. In the present study, we used the optical fractionator to estimate the number of neurons in the rat retrohippocampal region. The following estimates were obtained: 3.3 x 10(5) in presubicular layers II and III, 1.5 x 10(5) in parasubicular layers II and III, 2.2 x 10(5) in the combined pre- and parasubicular layers V and VI, 6.6 x 10(4) in medial entorhinal area (MEA) layer II, 1.3 x 10(5) in MEA layer III, 1.9 x 10(5) in MEA layers V and VI, 4.6 x 10(4) in lateral entorhinal area (LEA) layer II, 1.2 x 10(5) in LEA layer III, and 1.4 x 10(5) in LEA layers V and VI. A surprising finding was the large numbers of neurons in the pre- and parasubiculum, which indicate an important role of these areas in the control of the entorhino-hippocampal projection. A comparison of the numbers of neurons in the hippocampus and entorhinal areas in rats with similar estimates in humans revealed that gross input-output relations are largely conserved. Differences between rats and humans may be accounted for by more prominent entorhino-neocortical projections in primates and consequent increases in the number of neurons in the hippocampus and retrohippocampal region, which are dedicated to these projections.

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Visual association encoding activates the medial temporal lobe: A functional magnetic resonance imaging study

et al. 1997

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Perineuronal satellitosis in the human hippocampal formation

Cited by 32 publications

References 33 publications

Perineuronal satellite neuroglia in the telencephalon of New Caledonian crows and other Passeriformes: evidence of satellite glial cells in the central nervous system of healthy birds?

Perineuronal satellite neuroglia in the telencephalon of New Caledonian crows and other Passeriformes: evidence of satellite glial cells in the central nervous system of healthy birds?

Neuron numbers in the presubiculum, parasubiculum, and entorhinal area of the rat

Visual association encoding activates the medial temporal lobe: A functional magnetic resonance imaging study

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