Periodontal Regeneration Using the Mixture of Human Tooth-ash and Plaster of Paris in Dogs

Gu, Ha-Ra; Jang, Hyun-Seon; Kim, Su-Wan; Park, Joo-Cheol; Kim, Byung-Ock

doi:10.5051/jkape.2006.36.1.15

Cited by 3 publications

(1 citation statement)

References 34 publications

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“…In an osteoporosis model involving 60 rats, a mixture of dental ash and plaster accelerated new bone formation and was more stable than that in the control group (17) . Gu et al (37) used human dental ash to treat bone defects in dog alveolar bone and found the presence of osteoclasts in the surrounding tissue, indicating an active bone-remodeling process. Therefore, this material is simple, easy to obtain, convenient to use, and promotes bone healing.…”

Section: Discussionmentioning

confidence: 99%

Effect of Milled Tooth Powder versus β-tricalcium phosphate as Bone Grafts on Healing of Tooth Extraction Sockets of Rabbits: An Experimental Study

Youssef

Bayoumi²,

Hassan³

et al. 2022

Egyptian Dental Journal

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Aim: To compare the effects of milled tooth (MT) powder and β-tricalcium phosphate (β-TCP) on healing of extraction sockets in rabbits.Methods: Sixty healthy adult male rabbits were divided into four groups (n=15). After anesthesia the right mandibular first molars were extracted and the treated materials (β-TCP or MT) were gently applied to the extraction sockets forming two groups. In the positive (+ve) control group, sockets healed spontaneously. In the negative (-ve) control group, jaws were left without any interference. Five rabbits from each group were euthanized 10, 20, and 30 days after surgery. Specimens were prepared for light microscopic examination using hematoxylin and eosin, Masson's trichrome staining, and osteopontin. ANOVA was used to assess the statistical significance of the difference between more than two group means. Tukey's multiple comparisons and post-hoc tests were used to explore differences between the means of multiple groups.Results: Regarding osteoid tissue formation by Masson's trichrome staining, a highly significant difference recorded between -ve control, +ve control/10 d, β-TCP/20 d, MT/10 d, and MT/30 d groups. However, no significant differences were detected between the -ve control and +ve control, β-TCP/ 20 d, β-TCP/30 d, and MT/30 d groups. Higher expression of osteopontin were detected in the β-TCP/20 d and MT/30 d groups, and a highly significant difference was observed compared to the +ve control group.Conclusions: MT powder is a biocompatible osteoconductive graft material that can be used as bone graft material in tooth extraction socket healing.

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Section: Discussionmentioning

confidence: 99%

Effect of Milled Tooth Powder versus β-tricalcium phosphate as Bone Grafts on Healing of Tooth Extraction Sockets of Rabbits: An Experimental Study

Youssef

Bayoumi²,

Hassan³

et al. 2022

Egyptian Dental Journal

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Surface characterization and biological properties of regular dentin, demineralized dentin, and deproteinized dentin

Tabatabaei

Tatari

Samadi

et al. 2016

J Mater Sci: Mater Med

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Bone autografts are often used for reconstruction of bone defects; however, due to the limitations of autografts, researchers have been in search of bone substitutes. Dentin is of particular interest for this purpose due to high similarity to bone. This in vitro study sought to assess the surface characteristics and biological properties of dentin samples prepared with different treatments. This study was conducted on regular (RD), demineralized (DemD), and deproteinized (DepD) dentin samples. X-ray diffraction and Fourier transform infrared spectroscopy were used for surface characterization. Samples were immersed in simulated body fluid, and their bioactivity was evaluated under a scanning electron microscope. The methyl thiazol tetrazolium assay, scanning electron microscope analysis and quantitative real-time polymerase chain reaction were performed, respectively to assess viability/proliferation, adhesion/morphology and osteoblast differentiation of cultured human dental pulp stem cells on dentin powders. Of the three dentin samples, DepD showed the highest and RD showed the lowest rate of formation and deposition of hydroxyapatite crystals. Although, the difference in superficial apatite was not significant among samples, functional groups on the surface, however, were more distinct on DepD. At four weeks, hydroxyapatite deposits were noted as needle-shaped accumulations on DemD sample and numerous hexagonal HA deposit masses were seen, covering the surface of DepD. The methyl thiazol tetrazolium, scanning electron microscope, and quantitative real-time polymerase chain reaction analyses during the 10-day cell culture on dentin powders showed the highest cell adhesion and viability and rapid differentiation in DepD. Based on the parameters evaluated in this in vitro study, DepD showed high rate of formation/deposition of hydroxyapatite crystals and adhesion/viability/osteogenic differentiation of human dental pulp stem cells, which may support its osteoinductive/osteoconductive potential for bone regeneration.

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Comparison of Autogenous Tooth Materials and Other Bone Grafts

Zhang¹,

Li²,

Qi³

et al. 2021

Tissue Eng Regen Med

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Periodontal Regeneration Using the Mixture of Human Tooth-ash and Plaster of Paris in Dogs

Cited by 3 publications

References 34 publications

Effect of Milled Tooth Powder versus β-tricalcium phosphate as Bone Grafts on Healing of Tooth Extraction Sockets of Rabbits: An Experimental Study

Effect of Milled Tooth Powder versus β-tricalcium phosphate as Bone Grafts on Healing of Tooth Extraction Sockets of Rabbits: An Experimental Study

Surface characterization and biological properties of regular dentin, demineralized dentin, and deproteinized dentin

Comparison of Autogenous Tooth Materials and Other Bone Grafts

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