1982
DOI: 10.1111/j.1600-0714.1982.tb00148.x
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Peripheral ameloblastoma: an ultrastructural analysis

Abstract: Ultrastructural observations were compared for three different zones in a case of peripheral ameloblastoma, namely: the deep tumor islands, the “altered” surface epithelium overlying the tumor, and the transitional area between “normal” and “altered” covering epithelium. The possible origins and the behavior of this condition are discussed.

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Cited by 20 publications
(5 citation statements)
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“…Immunohistochemically, PA showed positive reactivity for AE1/AE3, KL1,34, E12, and MNF116 cytokeratin and negative staining for CK8, CK10, CK13, CK17, and CK18, are in accordance with the observation seen in human enamel organ [15] PA should be differentiated from peripheral reactive lesions such as pyogenic granuloma, epulis, papilloma, fibroma, peripheral giant-cell granuloma, peripheral odontogenic fibroma, peripheral-ossifying fibroma, Baden's odontogenic gingival epithelial hamartoma, and basal cell carcinoma [2]. The current treatment of choice is conservative supra periosteal surgical excision with adequate disease-free margins [2] .…”
Section: Discussionsupporting
confidence: 86%
“…Immunohistochemically, PA showed positive reactivity for AE1/AE3, KL1,34, E12, and MNF116 cytokeratin and negative staining for CK8, CK10, CK13, CK17, and CK18, are in accordance with the observation seen in human enamel organ [15] PA should be differentiated from peripheral reactive lesions such as pyogenic granuloma, epulis, papilloma, fibroma, peripheral giant-cell granuloma, peripheral odontogenic fibroma, peripheral-ossifying fibroma, Baden's odontogenic gingival epithelial hamartoma, and basal cell carcinoma [2]. The current treatment of choice is conservative supra periosteal surgical excision with adequate disease-free margins [2] .…”
Section: Discussionsupporting
confidence: 86%
“…Immunohistochemically, PA showed positive reactivity for AE1/AE3, KL1,34, E12, and MNF116 cytokeratin and negative staining for CK8, CK10, CK13, CK17, and CK18, are in accordance with the observation seen in human enamel organ [5]. Ameloblastomas, whether central or peripheral, are essentially devoid of CK7, CK8, CK10, CK18, CK20 [4, 6, 7], and epithelial membrane antigen [8].…”
Section: Discussionsupporting
confidence: 57%
“…The inability to identify, on an ultrastructural basis, the presence of a transitional “preameloblastomatous” zone, either in the altered epithelium or laterally at the junction between altered and normal gingival epithelium, precludes any definitive elusions on matter whether the tumor is derived from the oral mucosa or from remnants of “odontogenic” epithelium within the underlying connective tissue. Ultrastructural features were also similar to central ameloblastoma [5]. …”
Section: Discussionmentioning
confidence: 99%
“…Histopathologically, the continuity of tumor islands with the rete ridges of the surface epithelium has been a significant feature. 2,9,13,14 It has led to speculation about the origin of the lesion. Continuity was demonstrable after multiple sections were examined in three of the cases reported here.…”
Section: Discussionmentioning
confidence: 99%