Peripheral Blood Smear Contamination with <i>Helicosporium </i>Fungi Resembling Microfilaria

Yoon, Kui-Hyun

doi:10.3343/alm.2015.35.1.169

Cited by 4 publications

(3 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As part of the general features, 60 -62 these fungal spores are less than 100 µm in length and can vary from 1 to 2 µm in thickness. These organisms are usually coiled and typically form approximately 1.5 to 3 coils; conidia presented as thread forms or atypical helical shapes, however, can occur.…”

Section: Blood Smear Contaminantmentioning

confidence: 99%

“…These organisms are usually coiled and typically form approximately 1.5 to 3 coils; conidia presented as thread forms or atypical helical shapes, however, can occur. 60 The inner structure contains variable areas of darkly basophilic stained and unstained material, and no organization is observed internally. In contrast, microfilariae differ from Helicosporium-type conidia by being larger in size (3-10 µm × 163-315 μm) and a well-defined internal organization has been characterized.…”

Section: Blood Smear Contaminantmentioning

confidence: 99%

See 1 more Smart Citation

Proceedings of the 2019 National Toxicology Program Satellite Symposium

et al. 2019

View full text Add to dashboard Cite

The 2019 annual National Toxicology Program Satellite Symposium, entitled “Pathology Potpourri,” was held in Raleigh, North Carolina, at the Society of Toxicologic Pathology’s 38th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers’ talks along with select images that were used by the audience for voting and discussion. Various lesions and topics covered during the symposium included aging mouse lesions from various strains, as well as the following lesions from various rat strains: rete testis sperm granuloma/fibrosis, ovarian cystadenocarcinoma, retro-orbital schwannoma, periductal cholangiofibrosis of the liver and pancreas, pars distalis hypertrophy, chronic progressive nephropathy, and renal tubule regeneration. Other cases included polyovular follicles in young beagle dogs and a fungal blood smear contaminant. One series of cases challenged the audience to consider how immunohistochemistry may improve the diagnosis of some tumors. Interesting retinal lesions from a rhesus macaque emphasized the difficulty in determining the etiology of any particular retinal lesion due to the retina’s similar response to vascular injury. Finally, a series of lesions from the International Harmonization of Nomenclature and Diagnostic Criteria Non-Rodent Fish Working Group were presented.

show abstract

Section: Blood Smear Contaminantmentioning

confidence: 99%

Section: Blood Smear Contaminantmentioning

confidence: 99%

Proceedings of the 2019 National Toxicology Program Satellite Symposium

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Airborne contamination with the conidia of Helicosporium spp. and similar fungi may be mistaken for microfilariae, but they are significantly smaller than true microfilariae and lack associated internal nuclei (14). Synthetic fibers may also be mistaken for microfilariae; however, the absence of internal features should be an immediate indication of such artifacts.…”

Section: Morphologic Identificationmentioning

confidence: 99%

Diagnostic Identification and Differentiation of Microfilariae

2019

View full text Add to dashboard Cite

The morphologic similarities of the microfilariae and their infrequency in clinical specimens in settings of endemicity present challenges to clinical laboratories in maintaining competence for accurate identification and differentiation. We present here a review of the primary filarial nematodes causing human infection, including an illustrated key, which we hope will improve the diagnostic capabilities of hematologists, microbiologists, medical technologists, and similarly qualified laboratorians.

show abstract