Pharmacists and Pediatric Medication Adherence: Bridging the Gap

El-Rachidi, Sarah; LaRochelle, Joseph M.; Morgan, Jill A.

doi:10.1310/hpj5202-124

Cited by 84 publications

(68 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Studies in clinical settings among children with other conditions indicate that treatment non-adherence among carers is partly associated with a lack of knowledge on the nature of treatment. [10,23] Use of other foods during the treatment period will likely compromise the caloric and nutrient intake required for catch-up growth in acutely malnourished children. This may contribute to poor weight gain and consequently a longer stay in a programme.…”

Section: Articlementioning

confidence: 99%

Carers’ knowledge of treatment of severe acute malnutrition at Dadaab refugee complex, Kenya: A prospective cohort study

et al. 2020

View full text Add to dashboard Cite

This open-access article is distributed under Creative Commons licence CC-BY-NC 4.0. Globally, about 55 million children under the age of 5 years (10%) are undernourished. Of these, 19 million suffer from severe acute malnutrition (SAM). [1] SAM contributes to about one million deaths every year in children under the age of 5 years. [1,2] Most SAM cases are from sub-Saharan Africa and South Asia. [3] The prevalence of SAM is generally higher in emergency contexts and contributes to about half of the deaths in children under the age of 5 years in refugee camps. [4] Initially, therapeutic feeding centres treated SAM cases through inpatient care. They admitted all children with SAM, with or without medical complications. This approach was associated with high mortality and default rates. [4] To address setbacks associated with this approach, the community-based management of acute malnutrition (CMAM) model was globally adopted in 2007 and implemented the same year in Kenya. [5,6] CMAM entails treatment of SAM cases at community level using ready-to-use therapeutic foods. In this model, SAM cases without medical complications are treated as outpatients in an outpatient therapeutic feeding programme (OTFP) and those with medical complications are treated as inpatients at stabilisation centres (SCs). [7] Programmes that integrate the CMAM model in an existing health system are referred to as integrated management of acute malnutrition. [5] In Kenya, such integrated programmes are implemented in both rural areas and refugee camp settings using the same national treatment guidelines. However, despite successes being reported through the implementation of the CMAM model, poor treatment outcomes, such as high default rates and long recovery periods, are still being reported. [2,4,8] Studies from paediatric clinical settings suggest that carers' lack of understanding on the nature of treatment may contribute to poor adherence to treatment modalities. [9,10] No studies have assessed carers' understanding of the nature of treating acute malnutrition in a refugee population. The aim of this study was therefore to describe carers' knowledge of treating SAM at the Dadaab refugee complex. Methods Study setting The study was conducted between 21 May and 31 July 2015 at the Dadaab refugee complex in Garissa County, Kenya. The complex consists of four refugee camps, namely Hagadera, Dagahaley, Ifo I and Ifo II. The majority (97.5%) of the refugees are of Somalian nationality. [11] Two camps (Ifo I and Hagadera) were randomly selected from the four sites. At the time of the study, Hagadera had a population of ~106 751 adults and 21 351 children under the age of 5 years, while the Ifo camp had a population of 84 269 adults and 16 854 children under the age of 5 years. [12,13] CMAM services were provided by the International Rescue Committee and Islamic Relief Kenya. Each camp had a CMAM Background. Severe acute malnutrition causes half of the deaths in children under the age of 5 years in refugee camps. Objective. To describe carers' ...

show abstract

Section: Articlementioning

confidence: 99%

Carers’ knowledge of treatment of severe acute malnutrition at Dadaab refugee complex, Kenya: A prospective cohort study

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Pediatric medication adherence is a challenge in chronic disease medication management and pharmacists are well positioned to aid in improving adherence. A recent review highlighted the impact of nonadherence in children, discussing many barriers but also potential strategies to enhance adherence. Collaboration with the family, education of the patient and caregiver, and offering of various technology tools (all strategies that were utilized in our study) were outlined as ways that pharmacists can be involved with improving pediatric medication adherence.…”

Section: Discussionmentioning

confidence: 99%

Characterization of clinical pharmacy services in a pediatric HIV clinic

Morris

Briars

Kraus

2019

J Am Coll Clin Pharm

View full text Add to dashboard Cite

Objectives The objectives of this study were to characterize and analyze clinical pharmacists' interventions in a pediatric human immunodeficiency virus clinic. Methods This retrospective review assesses interventions documented by pediatric pharmacists. The percent of patients with an undetectable viral load at baseline, prior to implementation of pharmacy services, was compared with the viral load at a 7‐year follow‐up visit. Mean log10 viral loads at years 1 and 7 were compared to baseline and the mean change in viral load was compared. Results Pharmacists were involved with the care of 53 patients at 2257 visits documenting 8893 interventions. Recommendations to physicians accounted for 1316 (14.8%) of the interventions. Pharmacists documented 3176 (35.7%) interventions to patients/caregivers. One‐thousand and twenty‐eight (11.6%) interventions were educational concepts taught to patients/caregivers. Pharmacists provided 1107 (12.4%) adherence aids and conducted 669 (7.5%) adherence assessments. The percentage of patients with undetectable viral loads increased from 12.1% (4/33) to 65.8% (25/38) (P = 0.0094). The mean log10 viral load at years 1 and 7 were lower than those obtained prior to the first clinical pharmacy visit (year 1:3.95 ± 1.22 copies/mL vs 4.37 ± 1.09 copies/mL; P = 0.0042; year 7:2.88 ± 1.21 copies/mL vs 4.42 ± 1.11 copies/mL; P < 0.0001).The decrease in mean log10 viral load (viral load change) was significantly greater in year 7 compared with year 1 (P = 0.04). A clinically significant mean viral load decrease occurred each year from years 2 to 7. Conclusions In 7 years of pediatric clinical pharmacy services, thousands of interventions were documented. An increase in the number of patients with an undetectable viral load and improvements in mean log10 viral load occurred. These findings suggest that interventions by pediatric clinical pharmacists contributed to overall improvements in viral loads observed in this study. This analysis provides insight into the essential role of a clinical pharmacist in a pediatric HIV clinic.

show abstract

“…A orientação e manejo na administração por via oral para esse público devem ocorrer conforme a fase de vida para cada criança e à maneira que se desenvolvem cognitivamente. O farmacêutico pode e deve ajudar os pais e cuidadores com orientações sobre melhores práticas de usos, medicação adequada e técnicas para crianças conforme fase de desenvolvimento (El-Rachidi et al, 2017).…”

Section: Introductionunclassified

Cuidados farmacêuticos na adesão da terapia medicamentosa oral em pacientes onco-pediátricos

Simões¹,

Martins²,

Vieira³

et al. 2020

Pubsaúde

View full text Add to dashboard Cite

Introdução: No ano de 2018, o câncer Infantil no Brasil, segundo estimativa do INCA representou 12.500 novos casos de câncer e 2.704 mortes. A quimioterapia oral é cada vez mais utilizada, consistindo principalmente na redução de custos de hospitalização e via de administração evitando a necessidade de recorrer à via intravenosa. O apoio da família, amigos e cuidadores, assim como a orientação farmacêutica são muito importantes para que o paciente onco-pediátrico possa ter uma boa adesão à terapia medicamentosa oral. Este trabalho tem como objetivo promover uma revisão bibliográfica da literatura na identificação dos principais problemas relacionados à adesão da terapia medicamentosa oral em pacientes onco-pediátricos e cuidados farmacêuticos na orientação de uso de medicamentos na terapia oral. Revisão: Esta pesquisa foi realizada através da revisão de artigos científicos nas bases de dados de portais eletrônicos SciELO, Google Acadêmico, PubMed relacionados a adesão à terapia medicamentosa por via oral, pacientes onco-pediátricos e orientação farmacêutica. Para isto, foram utilizadas as palavras chaves: "adesão à medicação oral", "câncer pediátrico", "orientação farmacêutica" e seus equivalentes em língua estrangeira (inglês), que resultaram na listagem total de 16 artigos. Discussão e considerações finais: A adesão à terapia por via oral é uma das formas de tratamento da doença, alguns fatores podem influenciar a adesão, tais como: o comportamento do doente, sócios-demográfico como a idade, educação e nível de conhecimento das crianças, principalmente nas primeiras fases de vida, é preciso orientação e manejo no cuidado ao paciente onco pediátrico. O acompanhamento, orientação e monitoramento pelo profissional capacitado são fundamentais para cuidado do câncer pediátrico. Certamente problemas relacionados à adesão da terapia medicamentosa oral em pacientes onco-pediátricos, influenciam na resposta ao tratamento e sucesso da terapia. Palavras-chave: adesão à medicação oral, câncer pediátrico, orientação farmacêutica.

show abstract

Pharmacists and Pediatric Medication Adherence: Bridging the Gap

Cited by 84 publications

References 28 publications

Carers’ knowledge of treatment of severe acute malnutrition at Dadaab refugee complex, Kenya: A prospective cohort study

Carers’ knowledge of treatment of severe acute malnutrition at Dadaab refugee complex, Kenya: A prospective cohort study

Characterization of clinical pharmacy services in a pediatric HIV clinic

Cuidados farmacêuticos na adesão da terapia medicamentosa oral em pacientes onco-pediátricos

Contact Info

Product

Resources

About