Pharmacognostic and Phytochemical Characteristics of the Aerial Part of Salvia moorcroftiana Wall. ex Benth. Growing Wild in Kashmir Valley, India

Gani, Riehana; Bhat, Zulfiqar Ali; Dar, Mudasir A.; Shah, Zahida

doi:10.5530/phm.2019.1.7

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…[ 22 ]. Polyphenols and flavonoids are natural antioxidants and possess other pharmacological activities such as anticancer, anti-inflammatory, antianxiety, and antimicrobial [ 23 ]. The targeted extraction of plant metabolites possessing antibacterial properties can be obtained by using suitable solvents (in terms of polarity) for plant extraction [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Khan,

Wahab

et al. 2023

PLoS ONE

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Multi-drug resistant bacteria sometimes known as “superbugs” developed through overuse and misuse of antibiotics are determined to be sensitive to small concentrations of silver nanoparticles. Various methods and sources are under investigation for the safe and efficient synthesis of silver nanoparticles having effective antibacterial activity even at low concentrations. We used a medicinal plant named Salvia moorcroftiana to extract phytochemicals with antibacterial, antioxidant, and reducing properties. Three types of solvents; from polar to nonpolar, i.e., water, dimethyl sulfoxide (DMSO), and hexane, were used to extract the plant as a whole and as well as in fractions. The biosynthesized silver nanoparticles in all extracts (except hexane-based extract) were spherical, smaller than 20 nm, polydispersed (PDI ranging between 0.2 and 0.5), and stable with repulsive force of action (average zeta value = -18.55±1.17). The tested bacterial strains i.e., Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis were found to be sensitive to even small concentrations of Ag-NPs, especially P. aeruginosa. The antibacterial effect of these Ag-NPs was associated with their ability to generate reactive oxygen species. DMSO (in fraction) could efficiently extract antibacterial phytochemicals and showed activity against MDR bacteria (inhibition zone = 11–12 mm). Thus, the antibacterial activity of fractionated DMSO extract was comparable to that of Ag-NPs because it contained phytochemicals having solid antibacterial potential. Furthermore, Ag-NPs synthesized from this extract owned superior antibacterial activity. However, whole aqueous extract-based Ag-NPs MIC was least (7–32 μg/mL) as compared to others.

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Section: Introductionmentioning

confidence: 99%

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Khan,

Wahab

et al. 2023

PLoS ONE

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show abstract

“…(13). The polyphenols and flavonoids are natural antioxidants and possess other pharmacological activities such as anticancer, anti-inflammatory, antianxiety, and antimicrobial (14). The targeted extraction of plant metabolites possessing antibacterial properties can be obtained by using suitable solvents (in terms of polarity) for plant extraction (15).…”

Section: Introductionmentioning

confidence: 99%

Solvent based fractional biosynthesis, phytochemical analysis and biological activity of silver nanoparticles obtained from extract ofSalvia moorcroftiana

Khan¹,

Khan²,

Aasim³

et al. 2023

Preprint

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Multi-drug resistant bacteria sometimes known as “superbugs” developed through overuse and misuse of antibiotics are determined to be sensitive to small concentrations of silver nanoparticles. Various methods and sources are under investigation for the safe and efficient synthesis of silver nanoparticles having effective antibacterial activity even at low concentrations. We used a medicinal plant named Salvia moorcroftiana to extract phytochemicals with antibacterial, antioxidant, and reducing properties. Three types of solvents; from polar to nonpolar, i.e., water, dimethyl sulfoxide (DMSO), and hexane, were used to extract the plant as a whole and as well as in fractions. The biosynthesized silver nanoparticles in all extracts (except hexane-based extract) were spherical, smaller than 20 nm, polydispersed (PDI ranging between 0.2 and 0.5), and stable with repulsive force of action (average zeta value = -18.55±1.17). The tested bacterial strains i.e., Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis were found to be sensitive to even small concentrations of AgNPs, especially P. aeruginosa. The antibacterial effect of these AgNPs was associated with their ability to generate reactive oxygen species. DMSO (in fraction) could efficiently extract antibacterial phytochemicals and showed activity against MDR bacteria (inhibition zone = 11-12 mm). Thus, the antibacterial activity of fractionated DMSO extract was comparable to that of AgNPs because it contained phytochemicals having solid antibacterial potential. Furthermore, AgNPs synthesized from this extract owned superior antibacterial activity. However, whole aqueous extract based AgNPs MIC was least (7-32 µg/mL) as compared to others.

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Biogenic gold nanoparticles of Salvia species in dyes degradation and detection of lead(II)

Ihsan,

Qazi,

Jamila

et al. 2024

Int. J. Environ. Sci. Technol.

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Pharmacognostic and Phytochemical Characteristics of the Aerial Part of Salvia moorcroftiana Wall. ex Benth. Growing Wild in Kashmir Valley, India

Cited by 3 publications

References 9 publications

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Solvent based fractional biosynthesis, phytochemical analysis, and biological activity of silver nanoparticles obtained from the extract of Salvia moorcroftiana

Solvent based fractional biosynthesis, phytochemical analysis and biological activity of silver nanoparticles obtained from extract ofSalvia moorcroftiana

Biogenic gold nanoparticles of Salvia species in dyes degradation and detection of lead(II)

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