Phenytoin and Phenobarbitone Levels in Human Brain and Cerebrospinal Fluid

Sherwin, Allan L.; Sokolowski, Catherine

doi:10.1007/978-3-642-85921-2_28

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1977

1985

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Cited by 9 publications

(2 citation statements)

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“…Lederle quality control sera* were included in each assay at two dilutions corresponding to 5 and 20 ng DPH. 30 plasma samples containing DPH over the concentration range 0-35 mg/l (0-140 ,umol/l) were analysed by RIA and by gas-liquid chromatography (Sherwin et al, 1973) (Fig. 2).…”

Section: Methodsmentioning

confidence: 99%

Pharmacokinetic observations of phenytoin disposition in the newborn and young infant.

Loughnan¹,

Greenwald²,

Purton³

et al. 1977

Archives of Disease in Childhood

101

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Section: Methodsmentioning

confidence: 99%

Pharmacokinetic observations of phenytoin disposition in the newborn and young infant.

Loughnan¹,

Greenwald²,

Purton³

et al. 1977

Archives of Disease in Childhood

101

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“…The higher bind ing of phenytoin to white matter than to gray matter is believed to be due to its high myelin content (18,19). Thus, it would be important to learn whether Purkinje cells have greater protein or lipid contents than other neuronal cerebellar tissues.…”

Section: Resultsmentioning

confidence: 99%