Photodynamic Therapy for the Treatment of Tumor Ingrowth in Expandable Esophageal Stents

Scheider, David M.; Siemens, M; Cirocco, Maria; Haber, GB; Kandel, Gabor; Kortan, P; Marcon, Norman E.

doi:10.1055/s-2007-1004188

Cited by 45 publications

(25 citation statements)

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“…Local palliation with the aim to improve swallowing, short hospitalization, low complication rate, increase of KPS and quality of life, as well as economic aspects, especially in patients with a short life expactancy, are the goals of treatment of patients with advanced cancer of the cardia and the esophagus. PDT in the palliation of esophageal tumors as reported in the literature [14][15][16] is now a more and more accepted method and is used depending on its availability. However, there are some economic arguments against the use of PDT, especially in patients with a short life expectancy [17].…”

Section: Discussionmentioning

confidence: 99%

Hyperbaric oxygen and photodynamic therapy in the treatment of advanced carcinoma of the cardia and the esophagus

et al. 2000

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Section: Discussionmentioning

confidence: 99%

Hyperbaric oxygen and photodynamic therapy in the treatment of advanced carcinoma of the cardia and the esophagus

et al. 2000

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“…The average luminal obstruction was 86% which improved to 57% after treatment. At 6 months, half the patients had greater than a 50% reduction in endoluminal obstruction [15].…”

Section: Clinical Studies With Photodynamic Therapy For Advanced Lungmentioning

confidence: 97%

“…Scheider and colleagues [15] evaluated PDT for the treatment of tumor ingrowth in patients with esophageal stents. In this study, four patients with tumor ingrowth into self-expanding uncovered stents developed progressive dysphagia.…”

Section: Clinical Studies With Photodynamic Therapy For Advanced Esopmentioning

confidence: 99%

Role of photodynamic therapy in unresectable esophageal and lung cancer

2006

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The incidence of esophageal cancer has increased dramatically in the Western population in the last two decades. Many of these patients tend to present late in the disease course with symptoms of dysphagia and malnutrition. Thus a majority of patients at presentation may require palliation of their symptoms. Lung cancer is the most common cause of cancer related mortality in the United States. Similar to esophageal cancer, many patients present in advanced stages where surgical resection for cure may not be an option. Endobronchial obstruction from both primary and metastatic neoplasm causes significant morbidity. The modalities, which are currently available for palliation of symptoms include surgery, photodynamic therapy, dilation, external beam radiation, stents, Nd:YAG laser therapy, and brachytherapy. Each of these modalities has their specific advantages and drawbacks. In this article, we discuss the role of photodynamic therapy in the palliation of esophageal and lung cancer.

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“…Monopolar electrocautery and Nd:YAG laser treatment are associated with the risk of fracturing the stent filaments. Scheider et al [94], therefore, recommend the use of photodynamic therapy. These authors applied this therapeutic modality in 4 cases of tumor ingrowth into metal stents, obtaining good results.…”

Section: Tumor Ingrowth and Overgrowthmentioning

confidence: 99%

Stenting in Esophageal Strictures

Petruzziello

Costamagna²

2002

Dig Dis

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The interventional management of esophageal strictures remains, to date, an important clinical challenge. Stenting is probably the best palliation modality in patients with incurable esophagogastric carcinoma. Conversely, the use of esophageal stents is still relatively uncommon for the treatment of refractory benign strictures. In the last few years, several new stents have become available as a result of significant advances that have been made in terms of design and materials. This review focuses on the endoscopic use of esophageal stents in malignant and benign esophageal strictures, revisiting the different types of expandable stents presently available, the techniques, the results, and the complications of stent insertion and giving some practical advices. Future developments in the field of esophageal stenting are also discussed.

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Photodynamic Therapy for the Treatment of Tumor Ingrowth in Expandable Esophageal Stents

Abstract: The use of PDT to treat tumor ingrowth through self-expanding metal esophageal stents is effective and safe.

Cited by 45 publications

References 0 publications

Hyperbaric oxygen and photodynamic therapy in the treatment of advanced carcinoma of the cardia and the esophagus

Hyperbaric oxygen and photodynamic therapy in the treatment of advanced carcinoma of the cardia and the esophagus

Role of photodynamic therapy in unresectable esophageal and lung cancer

Stenting in Esophageal Strictures

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