Phototherapy for Cutaneous T-Cell Lymphoma

Marka, Arthur; Carter, Joi B.

doi:10.1016/j.det.2019.08.013

Cited by 14 publications

(10 citation statements)

References 48 publications

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“…In the early stages of cutaneous T cell lymphoma, besides topical steroids and nitrogen mustard (28), phototherapy can also be considered, PUVA and NB-UVB being first-line treatments. PUVA phototherapy seems to be associated with much more favorable results (29). A study conducted by Ahmad et al (30) showed the effectiveness of both NB-UVB phototherapy and PUVA phototherapy, registering complete remissions especially in the early stages (IA, IB) of cutaneous T cell lymphoma in 50 and 64% of patients, respectively (30).…”

Section: Indications For Phototherapy In Dermatologymentioning

confidence: 99%

Phototherapy in dermatological maladies (Review)

et al. 2022

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Since the introduction of modern phototherapy in 1903 by Nobel Prize-winner Niels Ryberg Finsen, the usage of this therapy in the medical field has grown, techniques have been refined and developed, and it has gained widespread acceptance. Psoriasis vulgaris, parapsoriasis, lichen planus, atopic dermatitis, neonatal jaundice, urticaria, morphea, vitiligo, granuloma annulare and cutaneous T cell lymphoma are only a few dermatological indications that come along with satisfactory results. Most often, it is a 2nd or 3rd line therapy being an alternative in more severe or refractory diseases. Despite the side effects that may occur after phototherapy, which are often minor, the benefits can be significant. Unfortunately, the absolute contraindications limit the use of this type of treatment and implicitly the management of these patients. The current review aimed to combine the recommendations of phototherapy in dermatology, the types of phototherapy that can be suitable for certain dermatological diseases and to emphasize its importance in certain conditions that are associated with significant remission rates.

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Section: Indications For Phototherapy In Dermatologymentioning

confidence: 99%

Phototherapy in dermatological maladies (Review)

et al. 2022

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“…The classic feature of MF is erythematous patches which eventually developing into plaques, tumors, and erythroderma. 56 Another type is Sezary syndrome (SS), manifested as erythroderma and the presence of circulating atypical T cells with or without lymphadenopathy. 57 MF is effectively treated using phototherapy.…”

Section: Cutaneous T Cell Lymphoma (Loe Ii)mentioning

confidence: 99%

Ultraviolet phototherapy for treatment of various dermatoses

Batubara

Paramitha

Pusponegoro

et al. 2021

JMedSci

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Ultraviolet (UV) radiation has been applied to treat many chronic skin diseases. Based on the wavelength, UV radiation consists of three types, namely ultraviolet C (UVC), ultraviolet B (UVB), and ultraviolet A (UVA). The types of UV that are widely used in dermatology are narrowband ultraviolet B (NB-UVB), broadband ultraviolet B (BB-UVB), UVA1, and psoralen combined with UVA (PUVA). The interaction between UV and the skin determines the effectiveness of phototherapy. The biological effects of UV are used in the management of inflammatory skin diseases, malignancies, and various rare dermatoses. Apart from these benefits, UV increases the risk of photoaging and skin cancer. Therefore, further researches are necessary to enhance the effectiveness and safety of phototherapy. This literature review discusses the role of phototherapy in various dermatoses other than psoriasis and vitiligo. ABSTRAKRadiasi sinar ultraviolet (UV) telah digunakan untuk pengobatan penyakit kulit kronik. Berdasarkan panjang gelombangnya, radiasi UV dibedakan dalam tiga jenis yaitu ultraviolet C (UVC), ultraviolet B (UVB), dan ultraviolet A (UVA). Jenis UV yang digunanakan secara luas dalam dematologi adalah narrowband ultraviolet B (NB-UVB), broadbrand ultraviolet B (BB-UVB), UVA1, dan psoralen dikombinasikan dengan UVA (PUVA). Interaksi antara UV dan kulit menentukan efektivitas fototerapi. Efek biologi UV digunakan dalam pengelolaan penyakit kulit inflamasi, malignansi, dan berbagai penyakit kulit yang jarang. Terlepas dari manfaatnya, UV meningkatkan risiko fotoaging dan kanker kulit. Oleh karena itu, penelitian lanjut diperlukan untuk meningkatkan efektivitas dan keamanan fototerapi. Kajian pustaka ini membicarakan peran fototerapi dalam berbagai penyakit kulit selain psoriasis dan vitiligo.

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“…This is expected to bring to the market several treatments at a lower risk, reduced cost, and less development time when compared to conventional drug development programs ( 202 – 204 ). One of the most interesting classes of molecules are psoralens, extensively studied as molecules to be employed in PUVA (Psoralen and Ultraviolet A)-therapy, a treatment extensively used in a variety of pathological conditions, including eczema, psoriasis, graft-vs.-host disease, vitiligo, mycosis fungoides, large-plaque parapsoriasis, and cutaneous T-cell lymphoma ( 205 ). It was in a study that found that 5-methoxypsoralen reduces P. aeruginosa -dependent IL-8 transcription in bronchial epithelial cell lines ( 206 ).…”

Section: Targeting Neutrophil Chemotaxis In Cf: Novel Molecules and Dmentioning

confidence: 99%