The failure of an unstable slope has the characteristics of sudden disaster, rapid sliding speed, and a wide range of influence. This study selected an unstable slope in Chongqing as the evaluation object, divided it into the strong-deformation zone and weak-deformation zone, and analyzed its formation mechanism and deformation failure mode. Macroscopic qualitative analysis was processed by the geological exploration method, the slope stability and the sliding thrust were quantitatively analyzed by the limit equilibrium method, and the sensitivity analysis was calculated and conducted on its shear strength parameters by laboratory tests and a field large shear test. The historical formation process of the slope was deduced, and suggestions for the prevention and control of unstable slopes were proposed. Studies show that the deformation mechanism of an unstable slope is a push type, its deformation is mainly concentrated in the southern area of the rear edge, and the width of the slope ground tensile crack is 1~30 cm, with a visible depth of 3~30 mm and an extension of 3~12 m. The shear strength of potential sliding zone soil in the weak-deformation zone is: cpw = 35.70 kPa, φpw = 14.80°, and in the strong-deformation zone it is: cps = 32.54 kPa, φps = 13.54°. The results show that the formation of a steep cliff by the artificial mining of sandstone is the main cause of slope deformation, the action of groundwater is the main triggering factor for slope deformation, and the inclined rock mass at the front edge is the key block for the deformation. The strong-deformation zone of the slope is in an unstable state under rainstorm, and the weak-deformation zone of the slope is basically-stable under rainstorm. Unstable slopes are prone to slide during a rainstorm period, which threatens the lives and properties of the residents and road traffic safety around the slope. The research results provide an important theoretical basis and data support for the accurate judgment and stability analysis of instability failure modes and for the further effective prevention and control of unstable slopes.