Physical properties and biological/odontogenic effects of an experimentally developed fast-setting α-tricalcium phosphate-based pulp capping material

Lee, Jun-Bong; Park, Su-Jung; Kim, Hyun‐Ha; Kwon, Yong-Ju; Lee, Kwang Won; Min, Kyung-San

doi:10.1186/1472-6831-14-87

Cited by 29 publications

(28 citation statements)

References 43 publications

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“…It is generally believed that high alkalinity of the material is mainly responsible for reparative dentin formation in an in vivo environment 46) . When a material with high pH such as calcium hydroxide or MTA is in contact with pulp tissue, it elicits a mild stimulation which is responsible for the odontogenic differentiation of dental pulp cells 47,48) . Consequently, reparative dentin is formed on the exposed pulp tissue by cells differentiated into odontoblast-like cell types.…”

Section: Discussionmentioning

confidence: 99%

Odontogenic effects of a fast-setting calcium-silicate cement containing zirconium oxide

et al. 2015

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A fast-setting calcium-silicate cement (Endocem) was introduced in the field of dentistry for use in vital pulp therapy. Similar to mineral trioxide aggregate (MTA), it contains bismuth oxide to provide radiopacity. Recently, another product, EndocemZr, which contains zirconium oxide (ZrO2) as a radiopacifier, was developed by the same company. In this study, the biological/odontogenic effects of EndocemZr were investigated in human primary dental pulp cells (hpDPCs) in vitro and on capped rat teeth in vivo. The biocompatibility of EndocemZr was similar to that of ProRoot and Endocem on the basis of cell viability tests and cell morphological analysis. The mineralization nodule formation, expression of odontogenic-related markers, and reparative dentin formation of EndocemZr group was similar to those of other material groups. Our results suggest that EndocemZr has the potential to be used as an effective material for vital pulp therapy, similar to ProRoot and Endocem.

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Section: Discussionmentioning

confidence: 99%

Odontogenic effects of a fast-setting calcium-silicate cement containing zirconium oxide

et al. 2015

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“…20 After mixing the materials in accordance with the manufacturer's instructions, initially the timer (Akai timer China stopwatch with an accuracy of one-hundredth of a second) was set to zero, and the timer was turned on…”

Section: Setting Timementioning

confidence: 99%

“…The head of the device was placed on a horizontal surface of material at intervals of 30 seconds for 5 seconds. 20 This device has two needles-the initial needle has a diameter of 2.12 mm and a weight of 113.4 gm, whereas the other needle has a diameter of 1.06 mm and a weight of 453.6 gm. The effect of needle dents shows the lack of hardening of the material examined.…”

Section: Setting Timementioning

confidence: 99%

Comparison of Compressive Strength and Setting Time of Four Experimental Nanohybrid Mineral Trioxide Aggregates and Angelus Mineral Trioxide Aggregate

Rahbar¹,

Tabari²,

Safyari³

et al. 2017

World Journal of Dentistry

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Aim: The present study was carried out with the objective of comparing the compressive strength and setting time of four experimental nanohybrid mineral trioxide aggregates (MTAs) and angelus MTA. Materials and methods:In this research, four experimental formulations of nanohybrid MTA (groups are with the base of Portland cement, containing nanoparticles of zirconia, aluminum oxide, titanium, nanosilica, and gypsum and bismuth trioxide) and angelus MTA were compared. Powder and water were mixed with the ratio determined by a factory for angelus MTA and were mixed at a ratio of 3:1 in experimental samples until the consistency of putty was reached. These were then placed in stainless steel cylinder generators, with a diameter of 4 mm and a height of 6 mm, for testing compressive strength, and in generators with a diameter of 10 mm and height of 2 mm to test setting time. The samples prepared were tested after 24 hours and a month using a strength-testing machine. A 135 G needle was used to test the initial setting time in the prepared samples, and a 456.5 G needle was used to test the final setting time. In the end, data were analyzed using Statistical Package for the Social Sciences (SPSS) software.Results: Experimental nanohybrid MTA P significantly showed the minimum setting time and experimental nanohybrid MTA Q showed the maximum setting time in 30 days (p < 0.05). Angelus MTA had greater compressive strength than the experimental materials in 24 hours. Clinical significance: Considering that experimental MTAs showed less setting time compared with the commercial type, experimental MTAs can be deployed in clinical usage. Conclusion

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“…Bu sebepten pulpa kaplamalarında ya da bir materyal altında liner olarak kullanılabilir. 34,36 Trikalsiyum fosfat siman, düĢük reaktivite gös-teren ve çözünebilen biyoseramik bir materyaldir. Kalsiyum salabilmesi ve biyouyumluluğu sayesinde odontoblastları uyarır ve böylece dentin köprüsü yapımını sağlar.…”

Section: Iģıkla Sertleģen Trikalsiyum Silikat Simanunclassified

Restorati̇f Di̇ş Tedavi̇si̇nde Pulpa Kaplamalari

Oğlakçı¹,

Arhun²,

Tuncer³

2015

Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi

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ÖZTravmaya uğramıĢ veya derin çürük lezyonlarına sahip diĢlere, pulpa vitalitesinin devam etmesi için vital pulpa tedavileri uygulanmaktadır. Günümüzde en çok uygulanan vital pulpa tedavisi prosedürü, pulpa kaplamasıdır. Remineralize olabilen dekalsifiye dentin dokusunun veya ekspoz olmuĢ pulpanın biyouyumlu bir materyalle örtülmesi ve tersiyer dentin yapımının uyarılması amaçlanır. Ġki tip pulpa kaplaması yöntemi vardır: Ġndirekt pulpa kaplaması ve direkt pulpa kaplaması. Ġndirekt pulpa kaplamalarında en çok kendi kendine sertleĢebilen kalsiyum hidroksit içerikli patlar ve çinko oksit öjenol simanlar kullanılmaktadır. Ayrıca, adeziv sistemler gibi alternatif pulpa kaplaması materyallerinin kullanımı da gündeme gelmiĢtir. Toz kalsiyum hidroksit, direkt pulpa kaplamalarında geleneksel olarak kullanılan en güvenilir materyal iken günümüzde mineral trioksit agregat altın standart olarak kabul edilir. Bu derlemenin amacı, pulpanın canlılığını korumak için açık pulpa üzerine veya pulpaya çok yaklaĢıldığında dentine yerleĢtirilen, yeni nesil biyouyumlu taban materyallerini (liner ve(ya) base) değerlendirmektir. Anahtar kelimeler: pulpa kaplaması, kalsiyum hidroksit, adeziv, mineral trioksit agregat, trikalsiyum silikat siman. PULPA KAPLAMALARITravmaya uğramıĢ (malokluzyon, atrizyon, abrazyon, erozyon, mekanik travma) veya derin çürük lezyonlarına sahip diĢlere, pulpa vitalitesinin devam etmesi için vital pulpa tedavisi uygulanmaktadır. En çok uygulanan vital pulpa tedavisi prosedürü pulpa kaplamasıdır. Koronal pulpanın uzaklaĢtırılması ise ABSTRACTThe vital pulp treatments are applied to the teeth with deep caries lesion or trauma for the purpose of maintaining the vitality of pulp. Nowadays, the most commonly performed treatment procedure is vital pulp capping. It is intended that the decalcified dentine which can be remineralized or exposed pulp are sealed with a biocompatible material and promotion of tertiary dentin formation. There are two types of pulp capping procedure: direct and indirect pulp capping. Traditionally, self-curing calcium hydroxide paste and zinc oxide-eugenol are carried out in indirect pulp capping. Furthermore, the use of alternative pulp capping materials such as adhesive systems has also been on the agenda. Even as, powdered calcium hydroxide conventionally used in direct pulp capping is the most reliable material; at the present time mineral trioxide aggregate is considered as the gold standard. Aim of this review is to evaluate new generation biocompatible base materials (liner and/or base) that used on exposed pulp or remained small amount of dentine over the pulp in order to maintain the vitality of the pulp. Keywords: pulp capping, calcium hydroxide, adhesive, mineral trioxide aggregate, tricalcium silicate cement.günümüzde pek tercih edilen bir tedavi seçeneği değildir.1,2 Çürüğün tamamen uzaklaĢtırılması sırasında çürük içermeyen, iĢleme bağlı (iatrojenik) veya travmatik yaralanmalarla, pulpanın açığa çıkma riski olan asemptomatik diĢlerde, remineralize olabilen dekalsifiye dentin do...

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Physical properties and biological/odontogenic effects of an experimentally developed fast-setting α-tricalcium phosphate-based pulp capping material

Abstract: Background: Recently, fast-setting α-tricalcium-phosphate (TCP) cement was developed for use in the pulp capping process. The aim of this study was to investigate the physical properties and biological effects of α-TCP cement in comparison with mineral trioxide aggregate (MTA).

Cited by 29 publications

References 43 publications

Odontogenic effects of a fast-setting calcium-silicate cement containing zirconium oxide

Odontogenic effects of a fast-setting calcium-silicate cement containing zirconium oxide

Comparison of Compressive Strength and Setting Time of Four Experimental Nanohybrid Mineral Trioxide Aggregates and Angelus Mineral Trioxide Aggregate

Restorati̇f Di̇ş Tedavi̇si̇nde Pulpa Kaplamalari

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