“…In 2002, it was proven that the use of estrogen plus progestogens (estrogen plus progestogen therapy [EPT]) was associated with an increased risk of breast cancer, 1 and, accordingly, its use has diminished both internationally 2,3 and in our country. 4,5 HT use varies with age, socioeconomic status, and education level, as well as several lifestyle factors. [6][7][8] Numerous studies have pointed out that the most common mammographic change that postmenopausal women experience after receiving HT is an increase in mammographic density (MD), [9][10][11] considered the main phenotype risk marker for breast cancer.…”