Physicochemical Properties and Bioactive Potential of a New Epoxy Resin-based Root Canal Sealer

Abstract

The aim of this study was to evaluate physicochemical properties and bioactive potential of Sealer Plus, in comparison with MTA Fillapex, Sealapex and AH Plus. Setting time, flow, and radiopacity were evaluated based on ISO 6876 Standard. Flow was also assessed in area (mm²). The solubility and volumetric change of the sealers were evaluated after 7 and 30 days of immersion in distilled water. Solubility was evaluated by the difference in mass of materials before and after immersion. Volumetric change was evaluated by using microcomputed tomography (micro-CT). The bioactive potential was observed by Scanning Electron Microscopy (SEM) after immersion in PBS. Data were compared using ANOVA and Tukey tests (α=0.05). Sealer Plus presented the shortest setting time (196 min.) and Sealapex the longest (912 min.) (p<0.05). AH Plus showed the highest radiopacity (9.5 mm Al) and MTA Fillapex the lowest (2.7 mm Al) (p<0.05). All the sealers presented flow in accordance with ISO 6876/2012 (>17 mm). Sealer Plus showed low solubility and volumetric change (<1%), and MTA Fillapex showed the highest solubility (>25%), and volumetric change (>4%) after all time intervals (p<0.05). MTA Fillapex was the only sealer that showed bioactive potential. In conclusion, Sealer Plus presented proper physicochemical properties. However, this sealer did not present a bioactive potential.

Evaluation of flow and filling of root canal sealers using different methodologies

“…Although the flow value of AH Plus was numerically higher than Sealapex and Fill Canal, the sealers had a statistically similar flow. The high flow of AH Plus was described in previous studies 12,13,[15][16][17][18] . The greater concentration of epoxy resin in AH Plus is considered the reason for its high flow rate 18 .…”

“…Ltda., Rio de Janeiro, RJ, Brazil) is a zinc oxide and eugenol-based sealer that is routinely used in the Brazilian dental practice 11 . Sealapex (SybronEndo, Glendona, CA, USA) is a root canal sealer based on calcium hydroxide 12 . Previous studies showed flow in accordance with the ISO 6876 for sealers based on calcium hydroxide, epoxy resin and zinc oxide and eugenol 12,13 .…”

“…Sealapex (SybronEndo, Glendona, CA, USA) is a root canal sealer based on calcium hydroxide 12 . Previous studies showed flow in accordance with the ISO 6876 for sealers based on calcium hydroxide, epoxy resin and zinc oxide and eugenol 12,13 . However, the comparison between flow and filling of these sealers was not assessed yet.…”

Atividade antimicrobiana de novos cimentos endodônticos biocerâmicos

“…Nessa condição de contato, o cimento resinoso AH Plus apresentou menor atividade antimicrobiana durante o período avaliado, fato também encontrado em estudos anteriores (Poggio, et al, 2017). O AH Plus apresenta baixos valores de pH e solubilidade (Mendes, et al, 2018;Tanomaru-Filho et al, 2019) quando comparado aos cimentos biocerâmicos, o que pode justificar sua menor ação antimicrobiana neste estudo. Os cimentos MTA Fillapex e Sealer Plus também apresentaram ação antimicrobiana significativamente maior do que o AH Plus e o controle.…”

Positive and negative properties of four endodontic sealant groups: a systematic review

“…Эпоксидные герметики имеют относительно короткое время полного отверждения, которое в среднем составляет 8 часов, при рабочем времени (первичного отверждения) около 4 часов [63].…”