2000
DOI: 10.1016/s0921-4488(00)00161-9
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Physiologic and biochemical effects of subarachnoidally administered xylazine and medetomidine in goats

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Cited by 40 publications
(66 citation statements)
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“…The decrease in RT observed in buffalo calves, after the administration of xylazine, medetomidine or their combinations with bupivacaine might have been caused by sedation, reduced metabolism, muscle relaxation and depression of the CNS (Kinjavdekar et al 2000). In addition, alpha-2 agonists may induce prolonged depression of thermoregulation as reported by Ponder & Clarke (1980) in cats.…”
Section: Discussionmentioning
confidence: 84%
“…The decrease in RT observed in buffalo calves, after the administration of xylazine, medetomidine or their combinations with bupivacaine might have been caused by sedation, reduced metabolism, muscle relaxation and depression of the CNS (Kinjavdekar et al 2000). In addition, alpha-2 agonists may induce prolonged depression of thermoregulation as reported by Ponder & Clarke (1980) in cats.…”
Section: Discussionmentioning
confidence: 84%
“…1,23 Although EA alone did not affect MAP and heart rate significantly, the decrease in MAP and heart rate was of a greater magnitude in goats given xylazine alone than in goats given the combination of EA plus xylazine, which showed that the EA improved MAP and heart rate. 1,23 Although EA alone did not affect MAP and heart rate significantly, the decrease in MAP and heart rate was of a greater magnitude in goats given xylazine alone than in goats given the combination of EA plus xylazine, which showed that the EA improved MAP and heart rate.…”
Section: Discussionmentioning
confidence: 94%
“…22,23 Obviously, this method is influenced by subjective factors. 22,23 Obviously, this method is influenced by subjective factors.…”
Section: Discussionmentioning
confidence: 99%
“…But it is not applicable for larger experimental animals (such as cattle and goats) because of their thick skin and hard hoof structure. The level of analgesia in these animals is commonly determined by scores based on an animal's response to a pinprick at a particular region [22, 23]. Obviously, this method is influenced by subjective factors.…”
Section: Discussionmentioning
confidence: 99%