Physiology of Sleep

Sembulingam, K; Sembulingam, Prema

doi:10.5005/jp/books/11696_77

Cited by 12 publications

(32 citation statements)

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“…Glucocorticoids prevent the inflammatory changes by inhibiting the migration of leukocytes and suppressing T cells [ 92 ]. The stimulation of epinephrine and adrenergic receptors may also exert some corticosteroid effects [ 93 ].…”

Section: Introductionmentioning

confidence: 99%

The role of hormones in the pathogenesis of psoriasis vulgaris

Roman

Constantin

Marina

et al. 2015

Medicine and Pharmacy Reports

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Psoriasis vulgaris is a chronic, common skin disease, which affects the patient’s quality of life to the highest degree. Several exogenous factors and endogenous hormonal changes may act as triggers for psoriasis.The skin possesses a true endocrine system, which is very important in multiple systemic diseases. A number of conditions are associated with psoriasis, and its severity can also be influenced by hormones. Even though the sex hormones and prolactin have a major role in psoriasis pathogenicity, there are a lot of other hormones which can influence the psoriasis clinical manifestations: glucocorticoids, epinephrine, thyroid hormones, and insulin.

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Section: Introductionmentioning

confidence: 99%

The role of hormones in the pathogenesis of psoriasis vulgaris

Roman

Constantin

Marina

et al. 2015

Medicine and Pharmacy Reports

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“…O pâncreas exócrino é constituído por ácinos, cada qual contendo uma única camada de células acinares com um lúmen no centro. Essas células contêm grânulos de zimogênios com enzimas digestivas que são liberadas através de um sistema de ductos interligados que desembocam no ducto de Wirsung (responsável por interligar o pâncreas ao duodeno) (Sembulingam & Sembulingam, 2012).…”

Section: Lista De Abreviaturas E Siglasunclassified

“…O pâncreas endócrino é formado pelas ilhotas pancreáticas (ilhotas de Langherans). Existem cerca de 1 a 2 milhões destas em um pâncreas humano, e sua função é liberar hormônios reguladores do metabolismo (insulina, glucagon, somatostatina e peptídeo pancreático entre outros) na corrente sanguínea (Sembulingam & Sembulingam, 2012).…”

Section: Lista De Abreviaturas E Siglasunclassified

“…As ilhotas pancreáticas são constituídas de células-beta produtoras de insulina, amilina e peptídeo-C (correspondendo a 73-75% da massa da ilhotas em roedores) células-(correspondendo a 18-20% da massa da ilhota) produtoras do hormônio glucagon, as células-δ (4-5% da massa da ilhota) produtoras do hormônio somatostatina, células-PP (1% da massa da ilhota) produtoras do hormônio polipeptídio pancreático e as células épsilon (<1% da massa da ilhota) (Sembulingam & Sembulingam, 2012).…”

Section: Ilhotas Pancreáticasunclassified

“…Além disso, o aumento da glicemia de forma continuada pode aumentar o risco de infecções (podendo facilitar o surgimento de periodontites), surgimento de ulceras, dificuldade de cicatrização e infecções nas regiões dos pés e amputações. As altas concentrações de glicose também provocam um aumento da osmolaridade e glicosúria acompanhada de poliúria (Hemmings & Egan, 2013;International Diabetes Federation, 2017;Sembulingam & Sembulingam, 2012…”

Section: Diabetes Mellitusunclassified

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Avaliação do papel de HSPB1 na modulação da autofagia induzida por PRL em células-beta

Silva¹

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Novel Microfluidic Colon with an Extracellular Matrix Membrane

Wang

Tanataweethum

Karnik

et al. 2018

ACS Biomater. Sci. Eng.

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Collagen is a key element of basal lamina in physiological systems that participates in cell and tissue culture. Its function is for cell maintenance and growth, angiogenesis, disease progression, and immunology. The goal of our present study was to integrate a micrometer resolution membrane that is synthesized out of rat-tail type I collagen in a microfluidic device with apical and basolateral chambers. The collagen membrane was generated by lyophilization. In order to evaluate the compatibility of the resulting membrane with organs-on-chips technology, it was sandwiched between layers of polydimethylsiloxane (PDMS) that had been prepared by replica molding, and the device was used to culture human colon caco 2 cells on the top of the membrane. Membrane microstructure, transport, and cell viability in the organs-on-chips were observed to confirm the suitability of our resulting membrane. Through transport studies, we compared diffusion of two different membranes: Transwell and our resulting collagen membrane. We found that mass transport of 40 kDa dextran was an order of magnitude higher through the collagen membrane than that through the Transwell membrane. Human colon caco 2 cells were cultured in devices with no, Transwell, or ECM membrane to evaluate the compatibility of cells on the ECM membrane compared to the other two membranes. We found that caco 2 cells cultured on the collagen membrane had excellent viability and function for extended periods of time compared to the other two devices. Our results indicate a substantial improvement in establishing a physiological microenvironment for in vitro organs-on-chips.

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Physiology of Sleep

Cited by 12 publications

References 0 publications

The role of hormones in the pathogenesis of psoriasis vulgaris

The role of hormones in the pathogenesis of psoriasis vulgaris

Avaliação do papel de HSPB1 na modulação da autofagia induzida por PRL em células-beta

Novel Microfluidic Colon with an Extracellular Matrix Membrane

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