Phytochemical and Biological Investigation of Hymenocallis littoralisSalisb.

Abstract

A phytochemical investigation of the bulbs and flowers of Hymenocallis littoralis SALISB., cultivated in Egypt, was carried out, which resulted in the isolation of four alkaloids, lycorine (1), hippeastrine (2), 11-hydroxyvittatine (3), and (+)-8-O-demethylmaritidine (4), and of two flavonoids, quercetin 3'-O-glucoside (5), and rutin (6). The volatile constituents of the plant flowers were analyzed for the first time by GC/MS, which led to the identification of 26 known compounds (Table 1). Finally, the antimicrobial activity of the petroleum ether extract of the flowers of H. littoralis was investigated.

Anti-candida activity by <i>Hymenocallis littoralis</i> extracts for opportunistic oral and genital infection <i>Candida albicans</i>

“…As to date, one study reported for the antimicrobial activity of the H. littoralis plant (Abou-Donia et al, 2008). Conversely, he stated that, the petroleum extract of the H. littoralis flower extract does not show activity for C. albicans strain.…”

“…Since 1920, there are several alkaloids that have been discovered from H. littoralis bulbs (Yew et al, 2010);such as littoraline, trazettine, omethyllycorinine, pretazettine, macronine, lycorine, homolycorine, lycorenine, hippeastrine, lycoramine, demethylmaritidine, haemanthamine, vittatine, and 5,6-dihydrobicolorine (Lweis, 1998), hippeastrine, 11-hydroxyvittatine and two flavonoids quercetin3'-Oglucoside and rutin were isolated (Abou-Donia et al, 2008). In addition, Abou-Donia and coworkers (2008) identified 26 known volatile constituents from H. littoralis flowers (Abou-Donia et al, 2008). The primarily isolated lycorine alkaloid from H. littoralis was proven to have antineoplastic, cytotoxicity and antiviral properties (Ioset et al, 2001;Yew et al, 2010).…”

Similarities Between Species of Ocimum and Mentha on the Basis of Phytochemical and Dna Quantification Study

“…Tannin possessed spasmolytic activity in smooth muscles cells, free radical scavenger and antioxidant. Flavonoids have antioxidant and antimicrobial properties while saponins are glycosides possessed antimicrobial and inhibit Na+ efflux, by blockage of the entrance of the Na+ out of the cell, reducing congestive heart failure 13,12 alkaloids have possessed analgesic, antisplasmodic and bactericidal activities, antioxidant and are useful in renal disorder 14,15 . The current investigation showed the presence of certain constituents in ethanolic extract of M. spicata and O. sanctum (O. gratissimum, O. tenuiflorum and Croton bonplandianus).…”

Preliminary responses of 2, 4-D and BAP on callus initiation of an important medicinal-ornamental Hymenocallis littoralis plants

“…For decades, many plants from the Amaryllidaceae plant family had been used as remedy for innumerable illnesses. As reviewed by Abou-Donia et al (2008), Hymenocallis salisb. genus was first phytochemically studied in 1920, which resulted in the isolation of lycorine.…”