“…We focus on the pooling problem because of its many industrial applications, including (Misener and Floudas, 2009): crude-oil scheduling (Lee et al, 1996;Li et al, 2007Li et al, , 2012a, water networks (Galan and Grossmann, 1998;Castro et al, 2007), natural gas production (Selot et al, 2008;Li et al, 2011), fixedcharge transportation with product blending (Papageorgiou et al, 2012), hybrid energy systems (Baliban et al, 2012), multi-period blend scheduling (Kolodziej et al, 2013), and mining (Boland et al, 2015). Solving the pooling problem is NP-hard (Alfaki and Haugland, 2013b;Baltean-Lugojan and Misener, 2018;Letsios et al, 2020), so deterministic global optimization solvers use algorithms such as branch & bound to solve the problem. Our goal with explicitly using special structure information is practically solving larger problem sizes.…”