Plasma Polymer Deposition: A Versatile Tool for Stem Cell Research

MacGregor, Melanie; Vasilev, Krasimir

doi:10.1002/9781119242642.ch8

Cited by 8 publications

(5 citation statements)

References 161 publications

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“…Recent studies established that plasma deposited POx (PPOx) films not only feature properties comparable to those of conventional POx films (e.g., biocompatibility and low biofouling) but also have additional attributes ascribed to the retention of the oxazoline ring . Most distinctively, PPOx films readily bind biomolecules at room temperature via the formation of covalent bonds with carboxylic acid groups, , which is highly valuable in many biomedical applications ranging from biosensing to cell therapies . To fully benefit from the unique properties of the PPOx films, it is important to mechanistically reveal how these coatings are deposited from the plasma phase.…”

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confidence: 99%

“…13 Most distinctively, PPOx films readily bind biomolecules at room temperature via the formation of covalent bonds with carboxylic acid groups, 14,15 which is highly valuable in many biomedical applications ranging from biosensing 16 to cell therapies. 17 To fully benefit from the unique properties of the PPOx films, it is important to mechanistically reveal how these coatings are deposited from the plasma phase. Herein, we used in situ mass spectrometry to explore the fragmentation of 2-methyl-2oxazoline (MeOx), Figure 1a, in the plasma phase across a useful input power range (2 to 50 W).…”

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confidence: 99%

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Secrets of Plasma-Deposited Polyoxazoline Functionality Lie in the Plasma Phase

et al. 2017

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confidence: 99%

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confidence: 99%

Secrets of Plasma-Deposited Polyoxazoline Functionality Lie in the Plasma Phase

et al. 2017

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“…The first degree of freedom when designing a plasma polymer is the monomer choice amongst a wealth of precursors [39]. Plasma polymers can be deposited from practically any compound volatile enough to be introduced into the reaction chamber.…”

Section: Plasma Polymersmentioning

confidence: 99%

Perspective on Plasma Polymers for Applied Biomaterials Nanoengineering and the Recent Rise of Oxazolines

MacGregor

Vasilev

2019

Materials

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Plasma polymers are unconventional organic thin films which only partially share the properties traditionally attributed to polymeric materials. For instance, they do not consist of repeating monomer units but rather present a highly crosslinked structure resembling the chemistry of the precursor used for deposition. Due to the complex nature of the deposition process, plasma polymers have historically been produced with little control over the chemistry of the plasma phase which is still poorly understood. Yet, plasma polymer research is thriving, in par with the commercialisation of innumerable products using this technology, in fields ranging from biomedical to green energy industries. Here, we briefly summarise the principles at the basis of plasma deposition and highlight recent progress made in understanding the unique chemistry and reactivity of these films. We then demonstrate how carefully designed plasma polymer films can serve the purpose of fundamental research and biomedical applications. We finish the review with a focus on a relatively new class of plasma polymers which are derived from oxazoline-based precursors. This type of coating has attracted significant attention recently due to its unique properties.

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“…Plasma treatment used in tissue or cell culture engineering is another interest in bioapplication [ 93 , 94 , 95 , 96 , 97 ]. Intranuovo et al [ 98 ] have investigated the behavior of osteoblast-like cell on a micro/nanopatterned coating that was deposited by RF plasma in a CVD system.…”

Section: Applicationsmentioning

confidence: 99%

Plasma-Based Nanostructuring of Polymers: A Review

2017

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There are various fabrication methods for synthesizing nanostructures, among which plasma-based technology is strongly competitive in terms of its flexibility and friendly uses, economy, and safety. This review systematically discusses plasma techniques and the detailed interactions of charged particles, radicals, and electrons with substrate materials of, in particular, polymers for their nanostructuring. Applications employing a plasma-based nanostructuring process are explored to show the advantages and benefits that plasma treatment brings to many topical and traditional issues, and are specifically related to wettability, healthcare, or energy researches. A short perspective is also presented on strategic plans for overcoming the limitations in dimension from surface to bulk, lifetime of surface functions, and selectivity for interactions.

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Plasma Polymer Deposition: A Versatile Tool for Stem Cell Research

Cited by 8 publications

References 161 publications

Secrets of Plasma-Deposited Polyoxazoline Functionality Lie in the Plasma Phase

Secrets of Plasma-Deposited Polyoxazoline Functionality Lie in the Plasma Phase

Perspective on Plasma Polymers for Applied Biomaterials Nanoengineering and the Recent Rise of Oxazolines

Plasma-Based Nanostructuring of Polymers: A Review

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