Plasma β-carotene response in humans after meals supplemented with dietary pectin

Abstract

The purpose of this study was to determine the effect of pectin on plasma response to beta-carotene in humans. Using a crossover design, we evaluated the effect on plasma beta-carotene in seven subjects when 12 g citrus pectin was added to a 2092 kJ (500 kcal) controlled meal with 25 mg beta-carotene. Plasma samples were collected at 0, 8, 30, 48, and 192 h after the meals. Plasma beta-carotene was quantified with the use of HPLC. The increase in plasma beta-carotene concentration was significantly reduced by pectin at 30 and 192 h (paired t test; P less than 0.005 and less than 0.05, respectively). Mean percent increase in plasma beta-carotene concentration at 30 h after the meal with beta-carotene was reduced by more than one-half when pectin was added to the meal. These results indicate that the inhibitory effect of pectin may provide one explanation for observations of reduced plasma beta-carotene response in humans after the ingestion of carotenoid-rich foods when compared with equivalent doses of beta-carotene supplements.

Mastication effects on carotenoid bioaccessibility from mango fruit tissue

“…Pectin from fruit matrices has been suggested to interfere with micelle formation by partitioning bile salts and fat in the pectin gel phase (Palafox-Carlos, Ayala-Zavala, & Gonzalez-Aguilar, 2011;Parada & Aguilera, 2007;Rock & Swendseid, 1992) that is necessary for the absorption of lipophilic carotenoids.…”

“…Epidemiological studies have shown an inverse correlation between consumption of carotenoid-rich fruits and vegetables, and the incidence of cancers of the gastrointestinal tract (Kant, Block, Schatzkin, & Nestle, 1992;Kiokias & Gordon, 2004;Mayne, 1996;Rock & Swendseid, 1992), cardiovascular diseases (Krinsky, 1998;Murr et al, 2009), diabetes (Yeum & Russell, 2002), some inflammatory diseases (Perera & Yen, 2007), as well as age-related macular degeneration (Snodderly, 1995). The most documented function of β-carotene is its provitamin A activity, with consequent health benefits, such as maintenance of epithelial function, embryonic development, and immune system function (Diplock, 1991).…”

Dietary Intake of Vitamin A and Macronutrients among Pregnant Women in Ngaoundere Town, Adamawa Region, Cameroon

“…Food fibers reduce the bioavailability of carotenoids by trapping them, or by interacting with biliary acids having as result increase in the fecal excretion of lipids and fat-soluble substances like carotenoids [28]. Therefore, the low consumption of fibers by these women could be beneficial for their pro-Vitamin A absorption.…”

Carotenóides como alternativa contra a hipovitaminose A

“…Os resultados obtidos por estudo realizado por Rock & Swendseid 33 indicaram um efeito inibitório da pectina, o que poderia justificar os reduzidos níveis plasmáticos de β-caroteno em humanos após a ingestão de alimentos ricos em carotenóides, quando comparados a doses equivalentes de suplementos de β-caroteno.…”